Results 61 to 70 of about 5,138,444 (292)

Modelling of Tirapazamine effects on solid tumour morphology [PDF]

open access: yes, 2011
Bioreductive drugs are in clinical practice to exploit the resistance from tumour microenvironments especially in the hypoxic region of tumour. We pre-sented a tumour treatment model to capture the pharmacology of one of the most prominent bioreductive ...
Kazmi, Nabila   +5 more
core   +1 more source

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao   +6 more
wiley   +1 more source

An omental teratoma in a young girl

open access: yesClinics and Practice, 2011
Teratoma is the most commonly encountered germ cell tumour among the most common ovarian tumours; however, teratomas of the omentum and mesentery are extremely rare. They are usually asymptomatic or can produce compressive symptoms.
Bhushan N. Wani   +3 more
doaj   +1 more source

Protein interactions in Xenopus germ plasm RNP particles [PDF]

open access: yes, 2013
Hermes is an RNA-binding protein that we have previously reported to be found in the ribonucleoprotein (RNP) particles of Xenopus germ plasm, where it is associated with various RNAs, including that encoding the germ line determinant Nanos1.
Nijjar, Sarbjit   +6 more
core   +2 more sources

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

A rare case of mediastinal nonseminomatous germ cell tumor with acute Megakaryocytic Leukemia

open access: yesJournal of Marine Medical Society, 2017
The most common extragonadal site of Nonseminomatous Germ Cell Tumours is the mediastinum. These are similar to their gonadal counterparts in histology but have a poorer prognosis.
G S Chowdhary, Malav Darshan Jhala
doaj   +1 more source

Séance du GERM/RITMO (02/12/2016)

open access: yes, 2016
Le vendredi 2 décembre 2016, de 10h à 13h Nous avons le plaisir de vous inviter à la prochaine réunion du GERM et du GDRI RITMO, Nous nous réunirons pour faire le point sur les avancées du dernier colloque à Rome, nous réfléchirons à la constitution d ...
germ
core   +1 more source

POSTER 27Analysis of reproductive parameters in men with testicular germ cell tumour

open access: yes, 2023
Problem This study aims to address sperm reproductive parameters and testis germ cell pathologies related to testicular germ cell tumour (TGCT) from both the clinical and experimental angle.
Zamecnik, Libor   +19 more
core   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu   +9 more
wiley   +1 more source

Osteolytic bone destruction resulting from relapse of a testicular tumour 23 years after inguinal orchiectomy and adjuvant chemotherapy: a case report

open access: yesJournal of Medical Case Reports, 2009
Introduction Late relapse of a testicular germ cell tumour is an uncommon occurrence. We report a case of osteolytic bone metastasis appearing 23 years after the initial treatment of a metastatic testicular mixed tumour (choriocarcinoma and embryonal ...
Kalaitzis Christos   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy