A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. [PDF]
Correct orientation of the mitotic spindle in stem cells underlies organogenesis. Spindle abnormalities correlate with cancer progression in germ line-derived tumors.
Bucko, Paula+8 more
core +1 more source
A novel dissolving microneedle platform preserves HPV virus‐like particle (VLP) immunogenicity by maintaining structural integrity, crucial for eliciting potent immune responses. Buccal administration induces robust immune response, high neutralizing antibody titers, and durable sterile protection across oral and vaginal mucosal sites.
Hyemi Kim+12 more
wiley +1 more source
Human Primordial Germ Cell Specification – Breakthrough In Culture and Hopes for Therapeutic Utilization [PDF]
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenKímfrumur eru forverar egg- og sáðfruma í mönnum, sem bera erfðaupplýsingar á milli kynslóða.
Erna Magnúsdóttir
core +1 more source
Recent Advances in Wide‐Bandgap Perovskite Solar Cells
Ubiquitous defects predominately account for photo‐instability and open‐circuit voltage losses in wide‐bandgap perovskite solar cells (WBG PSCs). This review comprehensively presents the underlying impact mechanisms, summarizes the advanced optimization strategies across various functional layers and their interfaces to develop efficient and stable WBG
Jianjun Mei, Feng Yan
wiley +1 more source
Nodal signaling regulates the entry into meiosis in fetal germ cells.
The mechanisms regulating the entry into meiosis in mammalian germ cells remain incompletely understood. We investigated the involvement of the TGF-β family members in fetal germ cell meiosis initiation.
Benoit Souquet+5 more
semanticscholar +1 more source
Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids [PDF]
Doxorubicin disrupts spermatogenesis by causing apoptosis of spermatogonia and primary spermatocytes. The aim of this study was to examine the effect of this agent on adult rat testicular lipids and their fatty acids.
Aveldaño, Marta Isabel+2 more
core +1 more source
Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo+5 more
wiley +1 more source
Binucleate germ cells in Caenorhabditis elegans are removed by physiological apoptosis.
Cell death plays a major role during C. elegans oogenesis, where over half of the oogenic germ cells die in a process termed physiological apoptosis. How germ cells are selected for physiological apoptosis, or instead become oocytes, is not understood ...
Stephan A Raiders+3 more
doaj +1 more source
Mutations in Nop60B, the Drosophila homolog of human Dyskeratosis congenita 1, affect the maintenance of the germ-line stem cell lineage during spermatogenesis [PDF]
Spermatogenesis in Drosophila is maintained by germ-line stem cells. These cells undergo self-renewing divisions and also generate daughter gonial cells, whose function is to amplify the germ cell pool.
DiNardo, Stephen+2 more
core +1 more source
Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications
This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin+8 more
wiley +1 more source