Results 211 to 220 of about 248,167 (261)
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Seminars in Reproductive Medicine, 2005
Transplantation of male germ line stem cells from a fertile donor to the testis of an infertile recipient restores donor-derived spermatogenesis in the recipient testis. The resulting sperm pass the donor genotype to the offspring of the recipient. Germ cell transplantation helped to elucidate the biology of male germ line stem cells and their niche in
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Transplantation of male germ line stem cells from a fertile donor to the testis of an infertile recipient restores donor-derived spermatogenesis in the recipient testis. The resulting sperm pass the donor genotype to the offspring of the recipient. Germ cell transplantation helped to elucidate the biology of male germ line stem cells and their niche in
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Hematology/Oncology Clinics of North America, 1992
The development of modern surgical staging and effective chemotherapy regimens has markedly improved outcome of treatment of ovarian germ cell tumors. Almost all patients with completely resected tumors will survive their disease. Those with tumors other than dysgerminoma should all receive adjuvant chemotherapy. Patients with stage IA dysgerminoma can
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The development of modern surgical staging and effective chemotherapy regimens has markedly improved outcome of treatment of ovarian germ cell tumors. Almost all patients with completely resected tumors will survive their disease. Those with tumors other than dysgerminoma should all receive adjuvant chemotherapy. Patients with stage IA dysgerminoma can
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2006
Primordial germ cells, which carry the responsibility for perpetuation of the species, are set aside from their somatic neighbors very early in mammalian embryonic development. The founder population of germ cells is rare and difficult to identify and isolate in quantities suitable for molecular and biochemical analysis, thereby highlighting the ...
Niels, Geijsen, George Q, Daley
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Primordial germ cells, which carry the responsibility for perpetuation of the species, are set aside from their somatic neighbors very early in mammalian embryonic development. The founder population of germ cells is rare and difficult to identify and isolate in quantities suitable for molecular and biochemical analysis, thereby highlighting the ...
Niels, Geijsen, George Q, Daley
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Molecular and Cellular Endocrinology, 2002
Transplantation of germ cells leads to restoration of spermatogenesis from spermatogonial stem cells. The original description of germ cell transplantation in 1994 has led to new approaches to explore many basic aspects of spermatogonial physiology.
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Transplantation of germ cells leads to restoration of spermatogenesis from spermatogonial stem cells. The original description of germ cell transplantation in 1994 has led to new approaches to explore many basic aspects of spermatogonial physiology.
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Surgical Clinics of North America, 2006
The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
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The category of germ cell tumors includes a broad array of histologic subtypes ranging from the benign, mature teratoma to the primitive, aggressive embryonal carcinoma (Box 1). These tumors share their origin in a primordial germ cell with multipotent capacity for differentiation along a variety of pathways.
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Embryonic Germ Cells: When Germ Cells Become Stem Cells
Seminars in Reproductive Medicine, 2006Embryonic germ cells (EGCs) are pluripotent stem cells derived from primordial germ cells (PGCs). PGCs are progenitors of adult gametes, which diverge from the somatic lineage between late embryonic to early fetal development. First derived in the mouse, EGCs have also been derived from human, chicken, and pig.
Candace L, Kerr +3 more
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Annals of Internal Medicine, 1981
Excerpt To the editor: The letters by Page (1) and Newcomer (2) in the May issue and the comments by other physicians in response to our article on unrecognized germ cell cancers (3) warrant a repl...
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Excerpt To the editor: The letters by Page (1) and Newcomer (2) in the May issue and the comments by other physicians in response to our article on unrecognized germ cell cancers (3) warrant a repl...
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2019
Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
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Germ cells undergo epigenome reprogramming for proper development of the next generation. The achievement of in vitro germ cell derivation from human and mouse pluripotent stem cells and further differentiation in a plane culture and in aggregation with gonadal somatic cells offers unprecedented opportunities for investigation of the germ cell ...
Kazuki, Kurimoto, Mitinori, Saitou
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Current Opinion in Oncology, 1999
The publication of the proceedings of Fourth Workshop on Carcinoma in situ was an impressive leap in our understanding of the interaction between prenatal and postpubertal factors in the development of germ cell cancer as well as increased insight into the molecular events that are involved in the development of these tumors. From this work, physicians
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The publication of the proceedings of Fourth Workshop on Carcinoma in situ was an impressive leap in our understanding of the interaction between prenatal and postpubertal factors in the development of germ cell cancer as well as increased insight into the molecular events that are involved in the development of these tumors. From this work, physicians
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Developmental arrest of germ cells in the pathogenesis of germ cell neoplasia
APMIS, 1998Clinical observations and epidemiological evidence suggest that important aetiopathological events that cause neoplastic transformation of the male germ cell may occur in fetal life or early infancy. The incidence of germ cell neoplasia is high in individuals with various disorders of gonadal development and sexual differentiation, such as gonadal ...
E, Rajpert-De Meyts +4 more
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