Results 91 to 100 of about 3,898,323 (346)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Top and bottom tensor couplings from a color octet scalar

open access: yes, 2017
We compute the one-loop contributions from a color octet scalar to the tensor anomalous couplings of top and bottom quarks to gluons, photons and W bosons.
Martinez, Roberto, Valencia, German
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

T-odd correlations from top-quark CEDM in lepton plus jets top-pair events

open access: yes, 2016
There exist several recent studies of the top-quark CEDM in the context of searching for CP violating signals in top-quark pair production at the LHC. Most of these studies constrain the CEDM either from deviations in the top-pair cross section from its ...
Hayreter, Alper, Valencia, German
core   +1 more source

Comparative analysis of genomic characteristics, fitness and virulence of MRSA ST398 and ST9 isolated from China and Germany [PDF]

open access: gold, 2021
Xing Ji   +11 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Ritorno radiativo per la misura di R: come e perche

open access: yes, 2003
The measurement of the pion form factor and, more generally, of the cross section for electron--positron annihilation into hadrons through the radiative return has become an important task for high luminosity colliders such as the $\Phi$- or $B$-meson ...
Rodrigo, German
core  

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Os grandes pícaros nas anécdotas e modismos alemáns e árabes. Un estudo comparativo [PDF]

open access: yesCadernos de Fraseoloxía Galega, 2009
Neste artigo realízase un estudo comparativo que nos ofrece unha idea xeral sobre Eulenspiegel e Goha, os pícaros máis célebres da literatura alemá e árabe, concretamente exipcia, e sobre as súas anécdotas, que son orixe dalgúns fraseoloxismos ...
Mona Noueshi
doaj  

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