Results 111 to 120 of about 3,848,803 (345)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
The Ethnology of Germany.-Part 3: The Migration of the Saxons. [PDF]
, 1878 Henry H. Howorth
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Eine neue kontrastiv-typologische Analyse der Onomatopoetika im Deutschen und Rumänischen [PDF]
Diversitate si Identitate Culturala in EuropaA NEW CONTRASTIVE-TYPOLOGICAL ANALYSIS OF ONOMATOPOEIA IN GERMAN AND ROMANIAN The seemingly obvious assumption that onomatopoeia faithfully reproduces the sounds of society and that these sounds are the same for all speakers is invalidated by the ...
Ioana Hermine FIERBINȚEANU
doaj
Anthropological Observations on German Prisoners of War. [PDF]
, 1919 F. G. Parsons
openalex +1 more source
Revue belge de philologie et d'histoire, 2012 Muhr Rudolf, Stickel Gerhard. German. In: Revue belge de philologie et d'histoire, tome 90, fasc. 3, 2012. Langues et littératures modernes. Moderne taal en letterkunde. pp. 889-914.
Muhr, Rudolf, Stickel, Gerhard
openaire +2 more sources
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Stylistyka, 2021 The goal of the article is to analyze the image of democracy in Polish and German feminism discourse, the way democracy is conceptualized and differentiated.
MONIKA GRZESZCZAK
doaj
The Tactics of Penetration: A Counterblast to German Numerical Superiority [PDF]
, 1914 J. F. C. Fuller
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EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source