Results 121 to 130 of about 1,603,617 (305)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
German-Texan Heritage Society Journal [PDF]
, 2012 Quarterly publication of the German-Texan Heritage Society providing information about news and events related to the work of the organization as well as stories, articles, genealogical data and other information of interest to members collected from ...
German-Texan Heritage Society +2 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Factors Shaping German Identity in the Settlements of Dombóvár and Its Surroundings
Modern GeográfiaDuring the censuses conducted between 1990 and 2011, the number of people identifying as German ethnicity consistently grew. Some researchers attributed this rise to a process of dissimilation.
Szenyéri, Zoltán
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2006 Öğrenmeye başladığımız ilk günden ulaştığımız yaşa kadar, sürekli bir şekilde yeni şeylerin isimlerini sözcük dağarcığımıza katıyoruz. 8 sözcük türünden biri olan sıfatlar, nesneleri algılamada, tanımlamada ve ayırt etmede önemli bir görev üstlenirler ...
Rıdvan Tunçel
doaj
Validation of the German version of the Perceived Cohesion Scale
International Journal of Occupational Medicine and Environmental HealthObjectives Team or group cohesion is a multifaceted construct with a variety of definitions and measurement instruments. However, most of these measures are context and group-specific and/or time-consuming.
Marietta Lieb +4 more
doaj +1 more source