Results 141 to 150 of about 823,331 (263)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Working conditions, job stress and work-related consequences among hospital employees-differences by professional group, working hours and job levels: A cross-sectional study. [PDF]

PLoS One
Hander NR, Erschens R, Klein T, Jarczok MN, Mulfinger N, Rieger MA, Junne F, Angerer P, Puschner B, Müller A, Küllenberg J, Maatouk I, Süß S, Gesang E, Ruhle S, Gündel H, Rothermund-Nassir E.   +16 more
europepmc   +1 more source

German-Argentine, German-Brazilian, German-Chilean: identities debate

, 2005
During the XIX century and in the pass of the first decades of the XX century, it was stablished projects of German colonization in Brazil, Argentina and Chile. They had big similarities in the three countries, as much in the objectives as in the agrarian structure model, as well as in the rural communities’ organization.
openaire   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

ABC8 Consensus: Assessment by a German Group of Experts. [PDF]

Breast Care (Basel)
Ditsch N, Untch M, Fasching PA, Briest S, Ettl J, Haidinger R, Lüftner D, Maurer C, Müller V, Park-Simon TW, Ruckhäberle E, Schem C, Schumacher-Wulf E, Harbeck N, Wuerstlein R.   +14 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

TESS 2.0-Adaptation of the German Version of the Toronto Extremity Salvage Score: Addition of an Item Regarding the Use of a Touchscreen and Keyboard in the Upper Extremity Questionnaire. [PDF]

J Clin Med
Hofer C, Kutscha-Lissberg LS, Windhager R, Hobusch GM, Trost C.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Erratum. [PDF]

J Turk Ger Gynecol Assoc
europepmc   +1 more source

The impact of doctorate-timing, whether undergraduate or postgraduate, on the experience of German doctors. [PDF]

BMC Med Educ
Al Naimi A, Hentrich A, Bahlmann F, Louwen F.   +3 more
europepmc   +1 more source