Results 51 to 60 of about 3,781,098 (345)
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Rhotics in Spanish as a foreign language: An intervention study with German–Turkish bilinguals
Strani Jezici, 2023 While German has one rhotic phoneme, the uvular fricative /ʁ/, which is vocalized to [ɐ] in syllable-final position, Spanish possesses two alveolar rhotics, the tap /ɾ/ and the trill /r/, which never undergo vocalization.
Christoph Gabriel +2 more
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
German Unification and the Demand for German M3 [PDF]
SSRN Electronic Journal, 1994 This paper estimates a demand equation for German M3 over the period 1971:1-1989:4, and studies its ability to predict all-German M3 during 1990:l-1992:4 and (a measure of) western German M3 during 1990:l-1994:l. Although the out-of-sample prediction errors appear serially correlated, the equation passes stability tests for the western German data ...
Stefan Gerlach, Stefan Gerlach
openaire +2 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Lingwistyka płci – nie kończąca się historia [PDF]
Linguistische Treffen in WrocławThe connections between gender as a biological category sexus, grammatical genus and socio-politicalcultural gender and language have always been present in scientific discussions to a greater or lesser extent.
Alina Jurasz
doaj +1 more source
The Route towards the ultimate network topology [PDF]
, 2016 In this talk I will try to summarize our quest for a realizable network topology that optimizes performance, cost, power consumption and partitionability.
Rodriguez, German
core
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Exploring the Influence of Personal Identity and Nostalgia on Memory Reconstruction in Thomas Brussig’s Sonnenallee (Sun Avenue) [PDF]
, 2011 Thomas Brussig ends his novel Sonnenallee with the following sentiment: Glueckliche Menschen haben ein schlechtes Gedaechtnis und reiche Erinnerungen [loose translation: Happy people have a bad memory and rich (or abundant) memories ].
German, Emily
core +2 more sources
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source