Results 71 to 80 of about 3,966,612 (344)

Loop-tree duality and quantum field theory in four dimensions

, 2016
Loop-tree duality allows to express virtual contributions in terms of phase-space integrals, thus leading to a direct comparison with real radiation terms. In this talk, we review the basis of the method and describe its application to regularize Feynman
Sborlini, German F. R.
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Connotative Potential of Deanthroponymic Semi-Suffixes in German

Филологический класс, 2022
The article studies denominations of persons in German with the second component – a feminine or masculine name. In German, persons are quite often named with the help of a complex method of word formation – semi-suffixation.
doaj   +1 more source

Relic gravitational waves and the generalized second law

, 2005
The generalized second law of gravitational thermodynamics is applied to the present era of accelerated expansion of the Universe. In spite of the fact that the entropy of matter and relic gravitational waves inside the event horizon diminish, the ...
Izquierdo, German, Pavon, Diego
core   +1 more source

German GPs’ Self-Perceived Role in the COVID-19 Pandemic: Leadership, Participation in Regional Services and Preferences for Future Pandemic Preparedness [PDF]

, 2023
Simon Kugai, Dorothea Wild, Yelda Krumpholtz, Manuela Schmidt, Katrin Balzer, Astrid Mayerböck, Birgitta Weltermann   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Constraints on anomalous color dipole operators from Higgs boson production at the LHC

, 2013
Physics beyond the standard model (SM) can be parameterized with an effective Lagrangian that respects the symmetries of the standard model and contains many operators of dimension six.
Hayreter, Alper, Valencia, German
core   +1 more source

The KIT:c.376G>A variant in German and Swiss alpacas (Vicugna pacos) with different coat colors [PDF]

, 2022
Kirsty Tan, Mia Roy, Eberhard Manz, Henrik Wagner, Patrik Zanolari, Cord Drögemüller, Gesine Lühken   +6 more
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source