Results 51 to 60 of about 1,134,243 (305)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

German Romantics Imagining India : Friedrich Schlegel in Paris and Roots of Ethnic Nationalism in Europe [PDF]

open access: yes, 2011
When, some two centuries ago, German Romantics turned their backs on modernity – industrialisation, urbanisation, commerce and secularisation – they turned to ancient India.
Dusche, Michael
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Functional Prestige in Sociolinguistic Evaluative Judgements Among Adult Second Language Speakers in Austria: Evidence from Perception

open access: yesLanguages
This study explores the perception of (Austrian) standard German and Austro-Bavarian dialect varieties by 111 adult speakers of German as a second language (L2) in Austria, tested through ‘smart’ and ‘friendly’ judgements in a matched-guise task.
Mason A. Wirtz, Andrea Ender
doaj   +1 more source

Combining data-driven MT systems for improved sign language translation [PDF]

open access: yes, 2007
In this paper, we investigate the feasibility of combining two data-driven machine translation (MT) systems for the translation of sign languages (SLs).
Bungeroth, Jan   +4 more
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Ist Standarddeutsch für Deutschschweizer eine Fremdsprache? Untersuchungen zu einem Topos des sprachreflexiven Diskurses

open access: yesLinguistik Online, 2005
This paper is concerned with the question, whether the status of Standard German in German-speaking Switzerland is adequately described as that of a foreign language.
Sara Hägi, Joachim Scharloth
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

The Lutheran-Protestant Last Supper as a Problem of Coordination and Positioning (the Case of Russia and Germany) [in German]

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2018
This paper examines the celebration of The Last Supper in three Lutheran worship services based on the methodology of multimodal interaction analysis.
Reinhold Schmitt, Anna A. Petrova
doaj   +1 more source

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