Results 101 to 110 of about 63,549 (243)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
German Literature in a New Century Trends, Traditions, Transitions, Transformations
Title page-German Literature in a New Century -- Contents -- Acknowledgements -- Introduction -- Part I-Trends -- Chapter 1-The litarary public sphere -- Chapter 2-Intellectuals in the public sphere -- Chapter 3-'Literatur Findet...Nicht Nur Auf Papier ...
Gerstenberger, Katharina. +1 more
core
The history of the horror genre in literature with a focus on German literature
, 2023 This bachelor thesis focuses on horror literature, with an emphasis on German horror literature. Its goal is to define the genre of horror in literature, to examine the most important points of its history, namely the most important authors and works, to
HRNČÍŘOVÁ, Eliška
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Concept of German-Arabic literature in the internal German-Syrian context. The work of Rafik Schami.
, 2016 This bachelor thesis deals with the German-Arabic literature, especially with its part - German- Syrian literature, which is in detail described on the work of Rafik Schami, the Syrian Author, who writes in German.
Vůchová, Tereza
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Czech literature and German expresionism 1910-1920
, 2009 The study discussing the influence of German expresionism on Czech literature in the years 1910 ...
Med, Jaroslav
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Brazilian literature written in German, and its criticism
Pandaemonium Germanicum: Revista de Estudos Germanísticos, 2016 This text aims to divulge a chronological and commented panorama of the critical studies published about the literature produced by German-speaking immigrants and their descendants in Brazil, arguing that this is a partial critique.
Celeste Ribeiro de Sousa
doaj