Results 91 to 100 of about 63,549 (243)
, 2015 Poster exhibition highlighting the history and process of German Unification in celebration of 25 years of German Unity.
Bauer, Esther +3 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
The Fool in Selected Works of German Literature
, 1967 iii, 49 p.This paper was originally meant to be a study of the development of the fool in German literature. However, in this I could not possibly have succeeded, for my knowledge of the literature is not extensive enough to trace the fool's ...
Kazeks, Inara Mara
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Introduction. Exploring the Great Divide. Animals and Humans in the German-Language Literature
, 2020 The recent emergence of the discipline of literary animal studies regards literature in itself as constitutive element of a history of knowledge. The discipline has led not only to the expansion of the corpus of texts traditionally connected with animals,
Bosco L., Latini M.
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Famous protagonists interfere with discourse topicality during pronoun resolution
Glossa PsycholinguisticsThe aim of the current study is to assess the impact of the wider discourse on pronoun interpretation. We specifically look at German demonstrative pronouns (dieser) in comparison to personal pronouns (er), investigating whether dieser-demonstratives are
Petra B. Schumacher +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The depiction of crowds in 1930s German narrative fiction
, 2011 This study of 1930s German fiction adds a new dimension to existing scholarship on the depiction of crowds in literature. Whereas previous surveys on the topic have predominantly focused on the crowd as a revolutionary phenomenon judged on the basis of ...
Harland, Rachel Fiona
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source