Results 71 to 80 of about 63,549 (243)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2010 This thesis is a critical analysis of W.G. Sebald‘s Luftkrieg und Literatur (On the Natural History of Destruction) and its reception in the German media and in scholarship. Sebald‘s essay caused a public debate in 1997 over the ethical implications of a
Lawson, C
core
Six Essays on the Young German Novel [PDF]
, 1972 In this study of the prose fiction of Das Junge Deutschland, the internal stresses and paradoxes of specific texts are examined and special attention is devoted to the unfulfilled strivings toward realism.
Sammons, Jeffrey L.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
La musica attraverso la poesia: Arnold Schönberg
Linguae &: Rivista di Lingue e Culture Moderne, 2015 Riassunto: Il saggio intende esplorare il pensiero musicale di Arnold Schönberg in relazione al contesto dell’avanguardismo letterario di inizio Novecento.
Runco Runco Maria Innocenza
doaj
Novella The Earthquake in Chile by Heinrich von Kleist in Serbian translations [PDF]
Zbornik Radova Filozofskog Fakulteta u PrištiniHeinrich von Kleist is one of the most well-known names of the 19th-century German literature, an author of dramatic works and novellas which are still widely received on the world's literary and theatrical stages.
Pasula Milica B.
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Paul Henry Gerber — physician, professor and poet from Königsberg
Слово.ру: балтийский акцентThe article explores the biography of Professor Paul Henry Gerber (1863-1919), a bright representative of the intellectual elite of Königsberg at the turn of the 19th-20th centuries.
Ilya О. Dementev
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source