Results 51 to 60 of about 1,448,711 (283)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Discourse Function of Differential Object Marking in Turkish

open access: yesLanguages
Differential Object Marking (DOM) is a cross-linguistic phenomenon in which the overt marking of direct objects of certain transitive verbs exhibits distinct morpho-syntactic properties.
Klaus von Heusinger   +1 more
doaj   +1 more source

German Prisoners of War in Canada, 1940–1946: An Autobiography-Based Essay [PDF]

open access: yes, 2019
The four years I spent in British and Canadian POW Camps offered ample time to study English Literature. This experience in particular had a decisive effect on my later career as university teacher of English literature.
Stanzel, Franz-Karl
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Il teatro di lingua tedesca tra Restaurazione e Naturalismo

open access: yesLea, 2014
This article outlines the development of nineteenth-century theatre from a sociological viewpoint, in particular, focusing on the coming of age of the Wiener Volkstheater under the direction of Raimund and Nestroy, as well as with the staging of works by
Rita Svandrlik
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Taking Up an Active Role: Emerging Participation in Early Mother–Infant Interaction during Peekaboo Routines

open access: yesFrontiers in Psychology, 2017
Dynamical systems approaches to social coordination underscore how participants' local actions give rise to and maintain global interactive patterns and how, in turn, they are also shaped by them.
Iris Nomikou   +6 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

German sentence accent revisited [PDF]

open access: yes, 2004
Results of a production experiment on the placement of sentence accent in German are reported. The hypothesis that German fulfills some of the most widely accepted rules of accent assignment— predicting focus domain integration—was only partly confirmed.
Féry, Caroline, Herbst, Laura
core  

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