Results 51 to 60 of about 63,549 (243)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The spaces of truth and cathedral window light
Literator, 1996 Major writers and painters of the Romantic period interpreted the church or cathedral in its organic and spiritual dimensions as a complex expression of a matured Christian civilization.
G. Gillespie
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Antiviral Combination Therapy with Interferon/Peginterferon Plus Ribavirin for Patients with Chronic Hepatitis C in Germany: A Health Technology Assessment Commissioned by the German Agency for Health Technology Assessment [PDF]
, 2010 Objective: The purpose of this health technology assessment (HTA), commissioned by the German Agency for HTA at the German Federal Ministry of Health and Social Security, was to systematically review the evidence on effectiveness and cost-effectiveness ...
Sroczynski, Gaby +3 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The Discourse Function of Differential Object Marking in Turkish
LanguagesDifferential Object Marking (DOM) is a cross-linguistic phenomenon in which the overt marking of direct objects of certain transitive verbs exhibits distinct morpho-syntactic properties.
Klaus von Heusinger +1 more
doaj +1 more source
Thirty-First Annual Bibliography 2017 (Contemporary German Literature Collection)
, 2018 The 31st bibliography for 828 volumes added to Washington University Libraries' Contemporary German Literature Collection. All published in 2017, these acquisitions include novels, poetry, short story collections, essays, autobiographical works, and ...
Paul Michael Lützeler +5 more
core +1 more source
, 2021 Formation and development of literary and cultural contacts, contributed to the domestic and International situation, growing interest in national literatures; acquaintance of the German reader with the life and work of outstanding Uzbek writers and ...
Imyaminova, S. (Shukhratkhon) +3 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Il teatro di lingua tedesca tra Restaurazione e Naturalismo
Lea, 2014 This article outlines the development of nineteenth-century theatre from a sociological viewpoint, in particular, focusing on the coming of age of the Wiener Volkstheater under the direction of Raimund and Nestroy, as well as with the staging of works by
Rita Svandrlik
doaj +1 more source