Results 61 to 70 of about 1,448,711 (283)

Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]

open access: yes, 2012
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Out of Time, Out of Space, Out of Species: Deictic Displacement of the Exiled Self in Hans Sahl’s “Der Maulwurf” (The Mole)

open access: yesHumanities, 2018
In Hans Sahl’s poem “Der Maulwurf” (The Mole), only the title gives an indication about the speaker’s species affiliation. The speaker of the poem suggests that he was transformed from a human into an animal.
Carla Swiderski
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

THE CHARACTER OF THE COLLECTOR AS A CREATIVE SUBJECT IN THE GERMAN AND RUSSIAN NOVELS AFTER 1980

open access: yesФилологический класс, 2019
The article deals with the actual problem of creative subject in the field of literary postmodernism, which solves the problem of self-identification. The postmodern “fragmented” subject is in the situation of “I-searching” in the “self-collection”.
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

JAZZ AS A PHENOMENON OF THE CULTURE OF REMEMBERANCE IN THE COMTEMPORARY GERMAN-LANGUAGE LITERATURE (MICHAEL KÖHLMEIER’S OCCIDENT AND FRIEDRICH CHRISTIAN DELIUS’ THE FUTURE OF BEAUTY)

open access: yesФилологический класс, 2019
Contemporary intermedial studies of belles-lettres focus on the interaction between literature and music, yet do not pay significant attention to the differentiation of music genres that literature refers to.
doaj   +1 more source

Iqbal and Goethe : a note [PDF]

open access: yes, 2011
The recourse to Goethe plays an important role in the work of Mohammad Iqbal (1873-1938), one of the few important writers from the Indian subcontinent who knew German literature.
Bhatti, Anil
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The Character of a Loafer in the Works by I. Beer, J. Von Eichen- dorff and I. Goncharov

open access: yesФилологический класс, 2022
The article is based on the idea of A. V. Mikhailov about the similarity of the character of a loafer of the Austrian baroque writer J. Beer and the Russian realist writer I. Goncharov. The German romantic J.
doaj   +1 more source

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