Results 131 to 140 of about 63,549 (243)
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Firm Heterogeneity and Choice of Ownership Structure: An Empirical Analysis of German FDI in India [PDF]
We contribute to the literature on the heterogeneity of multinational enterprises (MNEs) and the relevance of firm characteristics for analyzing the determinants of outward foreign direct investment (FDI).
Verena Lauber +3 more
core
West Meets East: Multicultural Perspectives in Two Works of German Youth Literature [PDF]
, 2008 This study examines the portrayal of multiculturalism in two works of German youth literature, Rafik Schami's Erzähler der Nacht (1989) and Aygen-Sibel Çelik's Seidenhaar (2007).
Harrington, Stefanie S
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
German language teachers’ attitudes towards reading and literature in Dutch schools
, 2018 This article analyses German language teachers’ attitudes towards reading and literature in Dutch schools. A survey among teachers revealed learning objectives, teaching methods and the frequency with which literature is taught in the lower classes of ...
van der Knaap, E.W. +2 more
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Ripe for a Diskursabenteuer: Jazz in Thomas Meinecke's Novels.
, 2013 The musician, broadcaster, and Suhrkamp novelist Thomas Meinecke, born 1955 in Hamburg, has emerged as an important voice in contemporary German literature since the mid-'1990s. I.ike some of his fellow authors at Suhrkamp, such as Rainakl Goetz, Andreas
Hurley, AW
core