Results 131 to 140 of about 10,163 (200)

Hypothalamic atrophy in progressive supranuclear palsy, assessed by convolutional neural network-based automatic segmentation. [PDF]

J Neurol
Kassubek J, Höglinger GU, Zůza A, Kreiser K, Roselli F, DESCRIBE-PSP Study Group, Müller HP.   +6 more
europepmc   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Genetic determinants of fatigue up to 2 years after radiotherapy in prostate cancer patients. [PDF]

Nat Commun
Heumann P, Aguado-Barrera ME, Jandu HK, Azria D, Briers E, Bultijnck R, Chang-Claude J, Choudhury A, Dunning AM, Fachal L, Fuentes-Ríos O, Gómez-Caamaño A, Gutiérrez-Enríquez S, Kaaks R, Kerns SL, Lambrecht M, Romero JCR, Rosenstein BS, De Ruysscher D, Schmidt ME, Sperk E, Stobart H, Symonds RP, Veldeman L, Veldwijk MR, Ward T, Webb A, West CML, Rancati T, Rattay T, Vega A, REQUITE Consortium, Talbot CJ, Seibold P.   +33 more
europepmc   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Chamber-specific chromatin architecture guides functional interpretation of disease-associated Cis-regulatory elements in human cardiomyocytes. [PDF]

Nat Commun
Haydar S, Bednarz R, Laurette P, Sobitov I, Díaz I Pedrosa N, Videm P, Lueneburg T, Kuß S, Lahm H, Dreßen M, Krane M, Schmidt C, Grüning BA, Voigt N, Streckfuss-Bömeke K, Gilsbach R.   +15 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Integration and validation of complementary ex vivo assays for functional precision oncology. [PDF]

NPJ Precis Oncol
Loboda A, Paluncic J, Freitas M, Weidmann M, Herter S, Zeiser C, Schulz JP, Jády A, Blattner-Johnson M, Autry RJ, Frese K, Lupar D, Schneider M, Imle R, Banito A, Glimm H, Witt O, Peterziel H, Kelm JM, Ball CR, Oehme I.   +20 more
europepmc   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

THE MEDICAL LIBRARY ASSOCIATION AND THE HIGH COST OF GERMAN MEDICAL PUBLICATIONS.

Bulletin of the Medical Library Association, 2006
openaire   +1 more source

Performance Evaluation of Large Language Models in Multilingual Medical Multiple-Choice Questions: Mixed Methods Study. [PDF]

JMIR Med Educ
Strasser LM, Anschuetz W, Dennstädt F, Hastings J.   +3 more
europepmc   +1 more source