Results 21 to 30 of about 8,866 (208)

Medizinbibliotheken 20XX. Zuverlässig, Zukunftsweisend, Unverzichtbar [Medical Libraries 20XX. Reliable, forward-looking, indispensible]

GMS Medizin – Bibliothek – Information, 2012
[english] The focus of the current issue 3/2012 of GMS Medizin – Bibliothek – Information is the annual conference 2012 of the German Medical Libraries Association in Aachen. The motto of the conference was “Medical Libraries 20XX.
Bauer, Bruno
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

„AGMB 2019: Gemeinsam neue Wege gestalten“. Jahrestagung der Arbeitsgemeinschaft für Medizinisches Bibliothekswesen (AGMB) e.V. vom 16. bis 18. September 2019 in Göttingen

GMS Medizin – Bibliothek – Information, 2019
In 2019 the annual meeting of the German Medical Library Association (AGMB) took place in Göttingen, Germany, from September 16 to 18. The meeting was organized by the Göttingen medical library of the University library of Göttingen. This year’s motto was “AGMB 2019: Shaping new paths together”.
openaire   +3 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Quo vadis AGMB? Ergebnisse der Online-Mitgliederbefragung 2019 sowie Ausblick auf mögliche Konsequenzen für die AGMB

GMS Medizin – Bibliothek – Information, 2019
Traditionally, the yearly conference of the Arbeitsgemeinschaft für Medizinisches Bibliothekswesen e.V. (German Medical Library Association) is the central continuing education event for librarians and information specialists working in all types of ...
Reimann, Iris, Semmler-Schmetz, Martina
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Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

10 Fragen von Bruno Bauer an Dietrich Nelle, den Interimsdirektor von ZB MED – Informationszentrum Lebenswissenschaften

GMS Medizin – Bibliothek – Information, 2018
ZB MED – Information Center for Life Sciences is the largest library worldwide in the field of life sciences. From October 2016 to June 2018 Dietrich Nelle was its interim managing director.
Bauer, Bruno, Nelle, Dietrich
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Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

THE DEVELOPMENT OF UKRAINIAN MEDICAL SCIENTIFIC ORGANIZATION THROUGH THE CENTURIES (ON THE 120th ANNIVERSARY OF ITS FOUNDING)

Праці Наукового товариства імені Шевченка. Медичні науки, 2018
Introduction. February 7th, 2018 marks 120 years since the foundation of the first Ukrainian medical scientific society “The Medical Commission of the Shevchenko Scientific Society.” Its original periodical journal  “Medical Collection” was initiated ...
Oksana Zayachkivska, Vassyl Lonchyna
doaj   +1 more source