Results 231 to 240 of about 335,205 (266)

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

open access: yesAdvanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han   +10 more
wiley   +1 more source

Long-term trends in Post-COVID severity: a machine learning analysis from the POP/COVIDOM cohort of the German NAPKON Cohort Network. [PDF]

open access: yesEClinicalMedicine
Gutzeit J   +24 more
europepmc   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

open access: yesAdvanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li   +10 more
wiley   +1 more source

A Reflection on Current Definitions of Critical Care and Critical Illness-A Narrative Review of the Literature. [PDF]

open access: yesNurs Crit Care
Sterr F   +9 more
europepmc   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

open access: yesAdvanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu   +14 more
wiley   +1 more source

Predatory journals: What can we do to protect their prey? [PDF]

open access: yesPLoS Med
Laine C   +15 more
europepmc   +1 more source

Genie in the bottle? a qualitative study of general practitioners' perspectives and information needs concerning digital mental health applications in Germany. [PDF]

open access: yesBMC Prim Care
Sahan F   +10 more
europepmc   +1 more source

Near-field and far-field exposures to radiofrequency electromagnetic fields and cancer risks in humans: a protocol for an umbrella review of epidemiological studies. [PDF]

open access: yesSyst Rev
Ziegler JL   +14 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy