Results 21 to 30 of about 21,696 (259)

Ekshumacijos aktų klastotės vertinant 1941 metų Utenos žydų sunaikinimą Rašės miške, ir ne tik.

open access: yesGenocidas ir Rezistencija, 2020
Rašės Park is located in Utena, in a north-eastern area of the town. The territory of the park covers the part of the valley of the Rašė River from Užpalių Street to the Kloviniai (Utena) pond.
Aleksandras Vitkus
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The Holocaust in Vilkaviškis County: the Fate of Pilviškiai Jewish Community in 1941

open access: yesGenocidas ir Rezistencija, 2011
Until summer 1941, Pilviškiai was one of the important locations populated with Litvaks (Lithuanian Jews) in Užnemunė (the area on the left bank of the River Nemunas) and in Vilkaviškis County.
Stanislovas Buchaveckas
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The All Lithuanian Conference of 5 April 1943: the Lithuanian Political Elite on the Crossroads of Collaboration and Resistance

open access: yesGenocidas ir Rezistencija, 2011
This article describes the political events in Lithuania under German occupation in the spring of 1943, when, thanks to the unified resistance of Lithuanian society, the establishment of an SS legion was foiled and the German occupiers started ...
Rimantas Zizas
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Kaunas Hard Labour Prison in the Years of Nazi Occupation (1941–1944)

open access: yesGenocidas ir Rezistencija, 2009
At the beginning of the war and Nazi occupation, with the efforts of the recreating Lithuanian administration, the system of prisons and forced labour camps, which operated in the years of the Republic of Lithuania and Soviet occupation, was renewed.
Arūnas Bubnys
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Kelmė and Vaiguva Jewish Communities and Their Perishing in 1941

open access: yesGenocidas ir Rezistencija, 2011
It is believed that Jews settled in Kelmė in the 15th century and in Vaiguva in the 18th century. In 1897, 2,710 of the 3,914 residents of Kelmė were Jews.
Stanislovas Buchaveckas
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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