Results 31 to 40 of about 338,748 (310)

Cinema programs as a source for research on historical film audiences. Berlin 1945–1949 [PDF]

open access: yes, 2015
In my paper, I analyse programs from cinemas in all four sectors of occupied Berlin from 1945 to 1949. I focus primarily on ads. Looking at cinema programs allows me to conduct research on local audiences by taking into consideration the social ...
Saryusz-Wolska, Magdalena
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Kaunas Hard Labour Prison in the Years of Nazi Occupation (1941–1944)

open access: yesGenocidas ir Rezistencija, 2009
At the beginning of the war and Nazi occupation, with the efforts of the recreating Lithuanian administration, the system of prisons and forced labour camps, which operated in the years of the Republic of Lithuania and Soviet occupation, was renewed.
Arūnas Bubnys
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Kelmė and Vaiguva Jewish Communities and Their Perishing in 1941

open access: yesGenocidas ir Rezistencija, 2011
It is believed that Jews settled in Kelmė in the 15th century and in Vaiguva in the 18th century. In 1897, 2,710 of the 3,914 residents of Kelmė were Jews.
Stanislovas Buchaveckas
doaj   +1 more source

Apprenticeship training in England: a cost-effective model for firms? [PDF]

open access: yes, 2018
In England, the government plans to incentivise spending of billions of pounds over the next few years promoting apprenticeships, with most of the finance raised from the apprenticeship levy on employers.
Joho, Eva, Wolter, Stefan
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Holocaust in Lithuania: Annihilation of the Jewish Communities of Palanga and Darbėnai Rural Areas of Kretinga County in Summer and Autumn 1941

open access: yesGenocidas ir Rezistencija, 2015
The article is dedicated to the annihilation of the Jewish communities of Palanga and Darbėnai rural areas of Kretinga County in summer and autumn 1941.
Alfredas Rukšėnas
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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