Results 111 to 120 of about 1,022,480 (312)

Links between self-monitoring data collected through smartphones and smartwatches and the individual disease trajectories of adult patients with depressive disorders: Study protocol of a one-year observational trial

open access: yesContemporary Clinical Trials Communications
Depression is highly recurrent and heterogenous in its individual course, requiring a personalized treatment approach. Patients today can collect large volumes of personal data via smartphones and smartwatches and may utilize them for their treatment and
Hanna Reich   +10 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Robust stability for stochastic Hopfield neural networks with time delays [PDF]

open access: yes, 2006
This is the post print version of the article. The official published version can be obtained from the link below - Copyright 2006 Elsevier Ltd.In this paper, the asymptotic stability analysis problem is considered for a class of uncertain stochastic ...
Arik   +31 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Heightened demand for mental health information resources during the SARS-CoV-2 pandemic in Germany: A retrospective longitudinal analysis of helpline calls

open access: yesJournal of Affective Disorders Reports
Background: The SARS-CoV-2 pandemic precipitated disruptions and limitations in medical services which led to changes in help-seeking behaviour. There was a surge the demand for crisis hotlines.
Jil Zippelius   +3 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Implementation of Funding for the German Socio-Economic Panel (SOEP): A Personal Recollection [PDF]

open access: yes
The SOEP success story was not conceivable at its inception. SOEP's institutionalization is therefore a lesson demonstrating that it is not always possible to say - as is so often required of research proposals today - how a project will develop before ...
Bernhard Schäfers
core  

Heidelberg University Library and its Special Subject Collection in Art History [PDF]

open access: yes, 2003
The article provides a short survey of the history and the services of the Special Subject Collection "Medieval and Modern Art History (up to 1945)" / "Art Studies" at the Heidelberg University Library funded by the DFG (German Research Foundation)
Effinger, Maria
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy