Results 41 to 50 of about 2,166 (262)
What Influences the Rate of Entry into Motherhood of Women Enrolled in Full-Time Education? A Difference-in-Differences Analysis of the Effect of the German Unification [PDF]
The purpose of this paper is to study the entry into motherhood of women in full-time education in East and West Germany before and after German unification.
Gwendolin J. Blossfeld
doaj
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
On the ‘burden’ of German unification
This paper investigates the causes of western Germany's remarkably poor performance since 1992. It challenges the view that Germany's poor economic record and marked deterioration in public finances since unification might be largely attributable to that
Jorg Bibow
doaj
The aim of the proposed investigation is to revise critically the German reform of the obligations (2002), establishing its main implications and relevance within the process of unification of European Law obligations and contracts, and especially of the
Rodrigo Barcia Lehmann +1 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Western European legal historiography deplores the 19th century as the age of destruction of the Romanrooted ius commune by national codes. In reality the French code civil, the Austrian ABGB and the German Pandectist jurisprudence effected rather a ...
Tomasz Giaro
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
La sfera pubblica tedesca nell’Europa della crisi
Contrary to the long pro-European tradition of post-war Germany, a silent repositioning of German governments and public opinion on EU topics has taken place in recent years.
Walter Privitera
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source

