Results 91 to 100 of about 327,377 (313)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
„In der englischen Sprache zu schreiben war eigentlich eine Zumutung für mich“
George Tabori (1914-2007), playwriter, stage director and Georg Büchner Prize recipient in 1992, is considered to be one of the most emblematic figures of German theater from the 1980s and 1990s.
Dirk Weissmann
doaj +1 more source
Reading the geographies of post-war British film culture through the reception of French film [PDF]
This paper examines the ways in which British specialist film culture anticipated and received the resumed supply of French films at the end of the Second World War.
Acland Charles +16 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Writing war, writing memory: the representation of the recent past and the construction of cultural memory in contemporary Bosnian prose [PDF]
Focusing on the work of Miljenko Jergović, Nenad Veličković, Alma Lazarevska, and Saša Stanišić, this paper examines how the representation of the recent past intertwines with the construction of collective memory in contemporary Bosnian prose.
Vervaet, Stijn
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Some Reflections on the Teaching of Military History in Canada [PDF]
Military History occupies a somewhat tenuous position in the curricula of Canadian universities. It is most often regarded as a kind of marginal enterprise to be offered by a faculty member who has some side-interest in these matters as a relief from the
Vogel, Robert
core +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
The author of the article tells about the experience of working with schoolchildren while studying the novel “Endless Book” by M. Ende.
doaj

