Results 101 to 110 of about 328,568 (309)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
German religious life as reflected historically in the German hymn [PDF]
, 1923 Thesis (M.A.)--Boston ...
Helland, Marie Elfrieda Julie
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Богословські роздуми: Східноєвропейський журнал богословʼя, 2016 With the application of comparative methodology, this article analyzes biblical allusions, reminiscences, paraphrases, direct and indirect quotations, and symbols in the poetry of Austrian, German, and Ukrainian writers (Georg Heym, Mykola Bazhan, Mykola
Tetiana MYKHALCHUK
doaj +1 more source
Existential angst: a reading of Saul Bellow's Seize the Day [PDF]
, 2011 TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão, Curso de Graduação em Língua e Literatura Estrangeira.RESUMO: Existencialismo é uma doutrina filosófica focada no ser humano em face da realidade, que vem ...
Souza, Sérgio de
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Rudolf Fuchs: An Underestimated Cultural Intermediary and Social Critic in Times of Conflict
HumanitiesRudolf Fuchs (1890–1942) was an influential figure in Prague’s early 20th-century literary scene as well as an intermediary between German and Czech literature at a time of intense social and political transformation. This study places Fuchs’ work within
Konstantin Kountouroyanis
doaj +1 more source
Migration, kvinder og skønlitteratur - Spændingsfeltet mellem hjemvé og hjem
Kvinder, Køn & Forskning, 1998 This article focuses on how social scientists can use fiction when studying migrant culture. The argument is that art e.g. fiction in different ways can illuminate personal experiences and feelings as well as themes and perspectives that are seldom ...
Yvonne Mørck
doaj +1 more source
Nature in German Culture: The Role of Writers in Environmental Debate [PDF]
, 2007 “Educated people make nature their friend”, reads a large sign on the picturesque remains of the old town wall in Marbach.1 The cobbled streets and crooked, half-timbered houses of Schiller’s birthplace nestle on the slopes above the Romantic river Neckar, and although the panorama from the Schiller Museum and National Literary Archive is dominated to ...
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source