Results 101 to 110 of about 257,440 (310)

Why Are East Germans Not More Mobile?: Analyzing the Impact of Local Networks on Migration Intentions [PDF]

open access: yes
Despite poor regional labour market conditions East Germans exhibit a rather limited willing-ness of leaving their home region. Applying an IV ordered probit approach and using the German Socio Economic Panel (SOEP), we test a local network explanation ...
Lutz Schneider, Peter Boenisch
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Strange Bedfellows and Their Grandchildren: German Literature as Evidence and Confession of Reunification

open access: yes, 2011
From Hegel to Merkel, from Bismarck to BMW, German culture has defined and re-defined itself through a cycle of reaction; thesis, antithesis, synthesis.
Rosenberg, Cory H.
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Nemški pogledi na vzroke razkola med Nemci in Slovenci

open access: yesDileme
In the middle of the 19th century, the first serious differences between the German and Slovenian political camps can be perceived. The rift between both camps in the 1860s, however, did not arise from national motives, but from political ones – due to ...
Valentin Areh
doaj   +1 more source

Social and Economic Characteristics of Financial and Blood Donors in Germany [PDF]

open access: yes
Surveys of the German Socio-Economic Panel Study (SOEP) have shown that Germans donated around 5.3 billion euros in 2009- right in the middle of the financial and economic crisis.
Eckhard Priller, Jürgen Schupp
core  

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

The Socio-Historical Contexts of Czech Anti-Semitism and Anti-German Sentiments Following the Establishment of the Czechoslovak Republic and their Reflection in Contemporary Caricatures

open access: yesSlovenský Národopis, 2019
The Czechoslovak Republic was created as the national state of the Czechs and Slovaks. Although it was based on the ethnic principle, the new state simultaneously assured relatively extensive rights for its national and religious minorities; in the Czech
Soukupová Blanka
doaj   +1 more source

The Social Logic of Bounded Partisanship in Germany: A Comparison of Veteran Citizens (West Germans), New Citizens (East Germans) and Immigrants [PDF]

open access: yes
That partisanship is bounded. Almost every West German, East German and immigrant never supports one or both of the major parties and most people vary support for their party by claiming no partisan preference.
Alan S. Zuckerman, Martin Kroh
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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