Results 101 to 110 of about 56,332 (302)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
, 1931 BoInformació extreta dels àlbums de l'EMC: Situació: Entre Caldes de Montbui i Terrassa. Facilitada Per: Germans Estorch.
Germans Estorch
core
The ANNALS of the American Academy of Political and Social Science, 1908 n ...
openaire +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Carretera de Cervelló, pujant a Vallirana
, 1936 BoTítol atorgat pel catalogador. Informació extreta de l'àlbum de l'EMC: Situació: Pujant a Vallirana, a l'esquerra de la carretera. Facilitada per: Germans Estorch.
Germans Estorch
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Lunau: THE GERMANS ON TRIAL [PDF]
, 1949 A Review of THE GERMANS ON TRIAL.
Michigan Law Review
core +2 more sources
Nemški pogledi na vzroke razkola med Nemci in Slovenci
DilemeIn the middle of the 19th century, the first serious differences between the German and Slovenian political camps can be perceived. The rift between both camps in the 1860s, however, did not arise from national motives, but from political ones – due to ...
Valentin Areh
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source