Results 21 to 30 of about 239,932 (252)

Economic and Political Reconstruction and Development of FRG in the Period after World War II

Historia i Polityka, 2021
In the first post-war years, the policy of the Western occupying powers towards Germany was aimed at preventing the economic revival of their former formidable competitor.
Mariusz Janik
doaj   +1 more source

The association of public health interventions regarding both infant sleep position and pertussis immunization with sudden infant death syndrome rates: an ecological study

BMC Pediatrics
Background Infections may play a role in the etiology of sudden infant death syndrome (SIDS), with Bordetella pertussis being a potential agent. The objective was to analyze the association of SIDS and infant pertussis hospitalization rates over time ...
Jacqueline Müller-Nordhorn, Amir Hakimhashemi, Stefan N. Willich, Sylvia Binting, Thomas Keil   +4 more
doaj   +1 more source

Trends in Women’s Educational Advantage and Divorce in East and West Germany

Comparative Population Studies
Couples in which wives have more education than their husbands have been found to be more likely than other couples to divorce. But this relationship varies across time and place.
Flavia Mazzeo, Christine Schwartz, Stefani Scherer, Agnese Vitali   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Changes in Birth Seasonality in East and West Germany, 1946-2017

Comparative Population Studies
Seasonal trends in fertility are found in several contexts and are affected by societal and environmental factors. This paper documents how birth seasonality in East and West Germany changed over time and, in particular, after 1989 and the onset of ...
Risto Conte Keivabu
doaj   +1 more source

Deux patriarcats différents ? Une « dispute entre sœurs » au sein du féminisme allemand au moment de la « réunification » des deux États allemands

Genre & Histoire, 2019
In analyzing the difficult meeting between West and East German feminists following “reunification” in the early 1990s, this article hopes to contribute to a better understanding of the dynamics of gender and the sexual politics in the partitioned ...
Cornelia Möser
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Incidence of maple syrup urine disease, propionic acidemia, and methylmalonic aciduria from newborn screening data

Molecular Genetics and Metabolism Reports, 2018
Incidence for the branched-chain intoxication-type disorders, maple syrup urine disease, propionic acidemia and methlymalonic aciduria is dependent on the population screened.
Kimberly A. Chapman, Gwendolyn Gramer, Sarah Viall, Marshall L. Summar   +3 more
doaj   +1 more source