Results 101 to 110 of about 3,120,902 (290)

Abstract 10.35 SILK A VERSATILE BIOMATERIAL FOR CLINICAL TRANSLATION

open access: yesPlastic and Reconstructive Surgery, Global Open, 2018
Tim Kornfeld, Christine Radtke, GERMANY
doaj   +1 more source

The Problem of Embryonic Stem Cell Research

open access: yesActa Medica Martiniana
Germany is quite restrictive regarding the importation and utilization of embryonic stem cells. To control stem cell research in Germany the Federal Government established in 2002 a Central Ethics Commission on Stem Cell Research.
Hans Schwarz
doaj   +1 more source

Gleaning insights from German energy transition and large-scale underground energy storage for China’s carbon neutrality

open access: diamond, 2023
Yachen Xie   +8 more
openalex   +1 more source

Cost-utility analysis of increasing uptake of universal seasonal quadrivalent influenza vaccine (QIV) in children aged 6 months and older in Germany [PDF]

open access: gold, 2022
Daniel Molnar   +11 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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