Results 31 to 40 of about 2,888,442 (218)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A questão de fundo do artigo diz respeito às possibilidades contidas na economia solidária para configurar vínculos não determinados pelo cálculo utilitário e materializar um regime singular entre distintos princípios operantes na vida econômica.
Luiz Inácio Germany Gaiger
doaj
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Soft Presentation of Hard News? A Content Analysis of Political Facebook Posts
The current media environment is primarily characterised by a large amount of information and, in contrast, rather fragmented audience attention. This is especially true for social media, particularly Facebook, which have become important news sources ...
Miriam Steiner
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Finland’s rapprochement to National-Socialist Germany as reaction against Winter War [PDF]
The aim of this article is to analyse the reasons behind the Finnish co-belligerency with Germany in the Operation Barbarossa. The investigation reveals the main reasons and key moments which contributed to Finnish rapprochement with Nazi Germany ...
Kalervo Hovi
doaj
The Weber/Putz ‘Proportionality Principle’: Determining Subsequent Performance Anew?
Although the European Court of Justice rendered its Weber/Putz judgment as long ago as three years, the turmoil since then in both academia and practice has not abated. Indeed, the significance of the ‘proportionality principle’ for European contract law
Thomas Hoffmann
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

