Results 171 to 180 of about 164,659 (242)

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, EarlyView.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Inter situ collections as a strategy to conserve an exceptional plant species from the Amazon rainforest. [PDF]

PLoS One
Escobar DFE, Gastauer M, Ramos SJ, Caldeira CF.   +3 more
europepmc   +1 more source

More‐than‐gender? Moving beyond gendered expectations of divergent learners in early childhood education

British Educational Research Journal, EarlyView.
Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley   +1 more source

A Practical Gut‐On‐Chip Workflow for Imaging‐Based Assessment of Epithelial Barrier Dynamics During E. coli Co‐Culture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The intestinal epithelium and its resident microbiota form a dynamic interface that is central to gut homeostasis, but this interface is difficult to model with conventional tools. Static Transwell cultures lack physiological fluid shear, whereas animal models are costly and poorly suited to quantitative, high‐content imaging.
Shih‐Wei Chiang, Chuan‐Yi Yang, Guan‐Yu Chen   +2 more
wiley   +1 more source

Dynamic diversification of lignan metabolism in sesame via coordinated oxygenation and glucosylation across germination. [PDF]

Proc Natl Acad Sci U S A
Harada E, Ohba Y, Ono E, Murata J, Toyonaga H, Shiraishi A, Azuma T, Waki T, Uegaki Y, Okamoto E, Hoshino A, Nakayama T, Wakasugi T, Yamamoto MP, Horikawa M.   +14 more
europepmc   +1 more source

Challenges and Future Directives of Synthetic Biology in Engineering Plant–Microbe Partnerships for Sustainable Agriculture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Synthetic biology has recently proven to be a valuable tool for enhancing agriculture even in the face of environmental and biological stresses. Understanding the challenges that militate synthetic biology will assist in ensuring safe, stable, and scalable crop production.
Ben Jesuorsemwen Enagbonma, Rebaona Reaobaka Molefe‐Madlaliso, Alaba Adewole Adebayo, Oghoye Priscilla Oyedoh, Godfrey Okainemen Oribhabor, Oluwaseun Emmanuel Shittu, Olubukola Oluranti Babalola   +6 more
wiley   +1 more source

Effects of Exogenous Selenium on Accumulations of Selenium, GABA and Antioxidant Activity of Chestnut During Germination. [PDF]

Molecules
Wang H, Liu W, Peng F, Zhang Z, Cao J, Shi J, He L, Jiang Y, Wang M, Yuan J.   +9 more
europepmc   +1 more source

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, EarlyView.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

New insights into the structure-based mechanism of <i>Bacillus subtilis</i> spore resistance to high hydrostatic pressure. [PDF]

Appl Environ Microbiol
Kang S, Gong Z, Zhang J, Meng Q, Li J, Lyu F, Rao L, Liao X.   +7 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source