Results 141 to 150 of about 11,317 (259)

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Optimization of post-ripening treatments for efficient germination of early-harvested winter wheat seeds under speed breeding. [PDF]

open access: yesFront Plant Sci
Yu X   +17 more
europepmc   +1 more source

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network‐level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare
Mohammad Reza Seyedtaghia   +4 more
wiley   +1 more source

A High‐Efficiency Yet Sustainable Fresh‐Keeping Strategy Inspired by Calyx of Physalis peruviana

open access: yesExploration, EarlyView.
This study presents a sprayable, calyx‐inspired food wrap engineered for safety and sustainability using handheld electrospraying. The wrap forms a health‐critical protective barrier with high antiviral and antibacterial efficacy, excellent breathability, and long‐term fresh‐keeping performance.
Yue Zhao   +17 more
wiley   +1 more source

Soluble Nanomedicine Against Soluble Neurosensitizers to Effectively Relieve Osteoarthritis Pain and Joint Damage

open access: yesExploration, EarlyView.
Osteoarthritis pain arises not only from joint damage but also from inflammation, abnormal bone changes, and excessive nerve activation inside the joint. In this study, we developed an injectable nanomedicine, LAC, that responds to the acidic environment of osteoarthritic joints to locally release two approved drugs, reducing inflammation, limiting ...
Junyan Liu   +12 more
wiley   +1 more source

Micro/Nanostructured Materials and Microfluidic Diagnostic Platforms Enable Multimodal Detection of Circulating Tumor Cells

open access: yesExploration, EarlyView.
Engineered micro/nanomaterials enable high‐efficiency CTC capture, release, and multimodal molecular profiling. Integrated with AI‐driven analytics, these platforms decode tumor heterogeneity and metastatic dynamics, advancing real‐time monitoring and precision oncology through DNA, RNA, and protein cross‐scale data fusion.
Hao Li   +7 more
wiley   +1 more source

Environmental Control for Edible Fungi Cultivation Based on Temporal Information and Deep Learning

open access: yesFood Bioengineering, EarlyView.
ABSTRACT Currently, there are still prevalent issues in greenhouse environmental regulation, such as response lag, low control accuracy, and difficulty in coping with sudden environmental disturbances. To achieve high‐precision and dynamic control of the edible fungi cultivation environment, this study proposes an edible fungi environmental control ...
Xiangyan Wang   +3 more
wiley   +1 more source

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