Results 151 to 160 of about 114,676 (292)

De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes

, 2021
Anne‐Perrine Foray, Sophie Candon, Sara Hildebrand, Cindy Marquet, Fabrice Valette, Coralie Pecquet, Sébastien Lemoine, Francina Langa‐Vives, Michaël Dumas, Peipei Hu, Pere Santamaría, Sylvaine You, Stephen Lyon, Lindsay Scott, Chun Hui Bu, Tao Wang, Darui Xu, Eva Marie Y. Moresco, Claudio Scazzocchio, Jean‐François Bach, Bruce Beutler, Lucienne Chatenoud   +21 more
openalex   +2 more sources

Low Impact of Germline Transposition on the Rate of Mildly Deleterious Mutation in Caenorhabditis elegans [PDF]

, 2006
Mattieu Bégin, Daniel J. Schoen
openalex   +1 more source

Somatic mutational profiles and germline polygenic risk scores in human cancer [PDF]

, 2021
Yuxi Liu, Alexander Gusev, Yujing J. Heng, Ludmil B. Alexandrov, Peter Kraft   +4 more
openalex   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source

Epidermal Growth Factor Receptor-mutated Lung Cancer as the Initial Manifestation of Germline TP53 Mutation Associated Cancer [PDF]

, 2018
Surabhi Pathak, Sunny Singh, Vatsala Katiyar, Susan McDunn   +3 more
openalex   +1 more source

Figure S2 from <i>BRCA2</i> Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors

, 2023
Annalisa Petrelli, Sabrina Rizzolio, Filippo Pietrantonio, Sara E. Bellomo, Matteo Benelli, Loris De Cecco, Dario Romagnoli, Enrico Berrino, Claudia Orrù, Salvatore Ribisi, Daniel Moya-Rull, Cristina Migliore, Daniela Conticelli, Irene M. Maina, Elisabetta Puliga, Violeta Serra, Benedetta Pellegrino, Alba Llop‐Guevara, Antonino Musolino, Salvatore Siena, Andrea Sartore‐Bianchi, Michele Prisciandaro, Federica Morano, Maria Antista, Uberto Fumagalli, Giovanni De Manzoni, Maurizio Degiuli, Gian Luca Baiocchi, Marco F. Amisano, Alessandro Ferrero, Caterina Marchiò, Simona Corso, Silvia Giordano   +32 more
openalex   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Hepatocellular carcinoma arising from adenoma with ARID1A mutation in an adolescent patient with ATM germline mutation. [PDF]

J Surg Case Rep
Drda E, Ali S, Fadel H, Sun B, Elfar W.
europepmc   +1 more source

Gastric neuroendocrine tumors in a BRCA2 germline mutation carrier: A case report. [PDF]

World J Gastrointest Oncol, 2023
Zhang HF, Zheng Y, Wen X, Zhao J, Li J.
europepmc   +1 more source

Germline HOXB13 Gene Mutation [PDF]

, 2020
openaire   +1 more source