Results 191 to 200 of about 114,676 (292)

Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 535-546, March/April 2025.
This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi, Laura Sarno, Antonio Angelino, Mariarosaria Motta, Raffaella Di Girolamo, Luigi Carbone, Marika Rovetto, Laura Letizia Mazzarelli, Gabriella Sglavo, Francesco D' Antonio, Ilenia Mappa, Daniele Di Mascio, Giuseppe Rizzo, Giuseppe Maria Maruotti   +13 more
wiley   +1 more source

Diverse mechanisms of leukemogenesis associated with PAX5 germline mutation. [PDF]

Leukemia
Bettini LR, Fazio G, Saitta C, Piazza R, Palamini S, Buracchi C, Rebellato S, Santoro N, Simone C, Biondi A, Cazzaniga G.   +10 more
europepmc   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

A rare germline mutation reverses the suppressive effect of <i>GPC5</i> thereby promoting lung adenocarcinoma development and tumorigenesis. [PDF]

Front Genet
Zheng Z, Zhao L, Zhao S, Wu Z, Wu N.
europepmc   +1 more source

Multigene Panel Sequencing Identifies a Novel Germline Mutation Profile in Male Breast Cancer Patients. [PDF]

Int J Mol Sci, 2023
Al Saati A, Vande Perre P, Plenecassagnes J, Gilhodes J, Monselet N, Cabarrou B, Lignon N, Filleron T, Telly D, Perello-Lestrade E, Feillel V, Staub A, Martinez M, Chipoulet E, Collet G, Thomas F, Gladieff L, Toulas C.   +17 more
europepmc   +1 more source

Escaping Constraints to Innovate: Maternal Neofunctionalization in a HoxB4 Duplicate

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Whole‐genome duplication in Xenopus laevis generated duplicated Hox genes that are largely constrained in sequence and developmental expression. However, HoxB4L uniquely acquired maternal expression through cis‐regulatory and protein structural divergence, illustrating how gene duplication enables transcription factors to escape pleiotropic constraints
Júlia de Lima Carvalho, José Caetano Silva‐Filho, Janaina Lima de Oliveira   +2 more
wiley   +1 more source

An Unexpected Finding of a PTPN11 Germline Mutation in a Patient With a Melanocytic Lesion With a Somatic MAP2K1 Mutation. Coincidence or Not? [PDF]

J Cutan Pathol
van der Woude S, Klein Wassink-Ruiter JS, Kluiver J, de Jonge M, Diercks GFH.   +4 more
europepmc   +1 more source

Vitamin C boosts DNA demethylation in TET2 germline mutation carriers. [PDF]

Clin Epigenetics, 2023
Taira A, Palin K, Kuosmanen A, Välimäki N, Kuittinen O, Kuismin O, Kaasinen E, Rajamäki K, Aaltonen LA.   +8 more
europepmc   +1 more source

Supplementary Methods from <i>BRCA2</i> Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors [PDF]

Annalisa Petrelli, Sabrina Rizzolio, Filippo Pietrantonio, Sara E. Bellomo, Matteo Benelli, Loris De Cecco, Dario Romagnoli, Enrico Berrino, Claudia Orrù, Salvatore Ribisi, Daniel Moya-Rull, Cristina Migliore, Daniela Conticelli, Irene M. Maina, Elisabetta Puliga, Violeta Serra, Benedetta Pellegrino, Alba Llop‐Guevara, Antonino Musolino, Salvatore Siena, Andrea Sartore‐Bianchi, Michele Prisciandaro, Federica Morano, Maria Antista, Uberto Fumagalli Romario, Giovanni De Manzoni, Maurizio Degiuli, Gian Luca Baiocchi, Marco F. Amisano, Alessandro Ferrero, Caterina Marchiò, Simona Corso, Silvia Giordano   +32 more
openalex   +1 more source

Epigenetic inflammatory memory and periodontal disease: Mechanisms and clinical significance for comorbidities

Journal of Periodontology, EarlyView.
Abstract Historically, immunological memory was considered an exclusive feature of adaptive immunity. However, innate immune cells have recently been shown to record and maintain epigenetically imprinted memory of earlier infectious or inflammatory challenges.
George Hajishengallis
wiley   +1 more source