Results 201 to 210 of about 123,315 (302)

Evidence of Site-Specific and Male-Biased Germline Mutation Rate in a Wild Songbird. [PDF]

Genome Biol Evol, 2023
Zhang H, Lundberg M, Tarka M, Hasselquist D, Hansson B.   +4 more
europepmc   +1 more source

Population size interacts with reproductive longevity to shape the germline mutation rate. [PDF]

Proc Natl Acad Sci U S A
Zhu L, Beichman A, Harris K.
europepmc   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Germline mutation rates and fine-scale recombination parameters in zebra finch. [PDF]

PLoS Genet
Prentout D, Bykova D, Hoge C, Hooper DM, McDiarmid CS, Wu F, Griffith SC, de Manuel M, Przeworski M.   +8 more
europepmc   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Germline mutation analysis and postoperative recurrence risk prediction in breast cancer patients from western China. [PDF]

Transl Oncol
Deng Z, Xiao X, Mou B, Wang J, Hu Q, Jiang J, Xie K, Zhang W, Li W, Chen B.   +9 more
europepmc   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

UroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

BRCA2 germline mutation carrier with five malignancies: a case report. [PDF]

Hered Cancer Clin Pract
Su E, Christinat Y, McKee T, Azzarello-Burri S, Jochum W, Fischer S, Rothermundt C.   +6 more
europepmc   +1 more source

Sporadic Hepatocellular Carcinoma in an Adolescent Harboring a Somatic CDH1 Mutation: A Case Report and Literature Review

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chang‐Wei Su, Peir‐In Liang, Shih‐Chang Chuang   +2 more
wiley   +1 more source

RNAi‐based functional genomics tools for the beet leafhopper using microinjection and nanoparticle‐based topical spray

Insect Science, EarlyView.
• First demonstration of functional RNAi in the beet leafhopper, Neoaliturus tenellus, using both dsRNA microinjection and star polycation nanoparticle‐mediated topical spray delivery.•Microinjection achieved over 90% knockdown of Gus and Pum3, revealing gene‐specific fitness effects on survival and fecundity in beet leafhopper.•Nanoparticle‐mediated ...
Jinlong Han, Maria Paula Mejia Alonzo, Meihua Cui, Katherine O. Puffer, Anna M. Wolff, Garret M. Miyake, Oliver T. Neher, Vamsi J. Nalam, Punya Nachappa   +8 more
wiley   +1 more source