Results 1 to 10 of about 181,660 (120)
Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways
Reproduction is highly dependent on environmental and physiological factors including nutrition, mating stimuli and microbes. Among these factors, microbes facilitate vital functions for host animals such as nutritional intake, metabolic regulation, and ...
Ritsuko Suyama +3 more
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Background Cadherins play a pivotal role in facilitating intercellular interactions between spermatogonial progenitor cells (SPCs) and their surrounding microenvironment.
Weixiang Song +8 more
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Germ Cell Drivers: Transmission of Preconception Stress Across Generations
Exposure to stress can accelerate maturation and hasten reproduction. Although potentially adaptive, the trade-off is higher risk for morbidity and mortality.
Korrina A. Duffy +5 more
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Background The scarcity of pluripotent stem cells poses a major challenge to the clinical application, given ethical and biosafety considerations. While germline stem cells commit to gamete differentiation throughout life, studies demonstrated the ...
Rui Wei +10 more
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Progress in germline stem cell transplantation in mammals and the potential usage
Germline stem cells (GSCs) are germ cells with the capacities of self-renewal and differentiation into functional gametes, and are able to migrate to their niche and reconstitute the fertility of recipients after transplantation.
Wen Zhang +4 more
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The Challenges in Developing Efficient and Robust Synthetic Homing Endonuclease Gene Drives
Making discrete and precise genetic changes to wild populations has been proposed as a means of addressing some of the world’s most pressing ecological and public health challenges caused by insect pests.
Sebald A. N. Verkuijl +5 more
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Haspin is a histone kinase that promotes error-free chromosome segregation by recruiting the chromosomal passenger complex (CPC) to mitotic and meiotic chromosomes.
Jommel Macaraeg +8 more
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HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans
Eukaryotic cells use guided search to coordinately control dispersed genetic elements. Argonaute proteins and their small RNA cofactors engage nascent RNAs and chromatin-associated proteins to direct transcriptional silencing.
Heesun Kim +6 more
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Germline predisposition to glial neoplasms in children and young adults: A narrative review
Gliomas are the most common malignancies of the central nervous system (CNS). A significant proportion of both low- and high-grade gliomas in children, adolescents, and young adults have specific genetic events which can be traced to the germline ...
Anirban Das +2 more
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The Piwil1 N domain is required for germ cell survival in Atlantic salmon
Genetic introgression of farmed salmon into wild populations can damage the genetic integrity of wild stocks and is therefore considered as an environmental threat. One possible solution is to induce sterility in farmed salmon.
Almeida F. L +11 more
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