Results 1 to 10 of about 181,660 (120)

Microbes control Drosophila germline stem cell increase and egg maturation through hormonal pathways

open access: yesCommunications Biology, 2023
Reproduction is highly dependent on environmental and physiological factors including nutrition, mating stimuli and microbes. Among these factors, microbes facilitate vital functions for host animals such as nutritional intake, metabolic regulation, and ...
Ritsuko Suyama   +3 more
doaj   +1 more source

E-cadherin maintains the undifferentiated state of mouse spermatogonial progenitor cells via β-catenin

open access: yesCell & Bioscience, 2022
Background Cadherins play a pivotal role in facilitating intercellular interactions between spermatogonial progenitor cells (SPCs) and their surrounding microenvironment.
Weixiang Song   +8 more
doaj   +1 more source

Germ Cell Drivers: Transmission of Preconception Stress Across Generations

open access: yesFrontiers in Human Neuroscience, 2021
Exposure to stress can accelerate maturation and hasten reproduction. Although potentially adaptive, the trade-off is higher risk for morbidity and mortality.
Korrina A. Duffy   +5 more
doaj   +1 more source

A rapid and stable spontaneous reprogramming system of Spermatogonial stem cells to Pluripotent State

open access: yesCell & Bioscience, 2023
Background The scarcity of pluripotent stem cells poses a major challenge to the clinical application, given ethical and biosafety considerations. While germline stem cells commit to gamete differentiation throughout life, studies demonstrated the ...
Rui Wei   +10 more
doaj   +1 more source

Progress in germline stem cell transplantation in mammals and the potential usage

open access: yesReproductive Biology and Endocrinology, 2022
Germline stem cells (GSCs) are germ cells with the capacities of self-renewal and differentiation into functional gametes, and are able to migrate to their niche and reconstitute the fertility of recipients after transplantation.
Wen Zhang   +4 more
doaj   +1 more source

The Challenges in Developing Efficient and Robust Synthetic Homing Endonuclease Gene Drives

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Making discrete and precise genetic changes to wild populations has been proposed as a means of addressing some of the world’s most pressing ecological and public health challenges caused by insect pests.
Sebald A. N. Verkuijl   +5 more
doaj   +1 more source

Genetic analysis of Caenorhabditis elegans Haspin-like genes shows that hasp-1 plays multiple roles in the germline

open access: yesBiology Open, 2022
Haspin is a histone kinase that promotes error-free chromosome segregation by recruiting the chromosomal passenger complex (CPC) to mitotic and meiotic chromosomes.
Jommel Macaraeg   +8 more
doaj   +1 more source

HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans

open access: yeseLife, 2021
Eukaryotic cells use guided search to coordinately control dispersed genetic elements. Argonaute proteins and their small RNA cofactors engage nascent RNAs and chromatin-associated proteins to direct transcriptional silencing.
Heesun Kim   +6 more
doaj   +1 more source

Germline predisposition to glial neoplasms in children and young adults: A narrative review

open access: yesGlioma, 2021
Gliomas are the most common malignancies of the central nervous system (CNS). A significant proportion of both low- and high-grade gliomas in children, adolescents, and young adults have specific genetic events which can be traced to the germline ...
Anirban Das   +2 more
doaj   +1 more source

The Piwil1 N domain is required for germ cell survival in Atlantic salmon

open access: yesFrontiers in Cell and Developmental Biology, 2022
Genetic introgression of farmed salmon into wild populations can damage the genetic integrity of wild stocks and is therefore considered as an environmental threat. One possible solution is to induce sterility in farmed salmon.
Almeida F. L   +11 more
doaj   +1 more source

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