Results 31 to 40 of about 234,487 (302)
Retinoblastoma in twins: Risk assessment of genotypic variants
Indian Journal of Ophthalmology, 2021 Purpose: To describe methods of risk assessment in twins with retinoblastoma (RB). Methods: A case series of four RB probands with a twin sibling. Family status, clinical presentation, and RB1 germline status-based risk assessment were analyzed. Results:
Vishal Raval +5 more
doaj +1 more source
G3: Genes, Genomes, Genetics, 2017 Mi2 proteins are evolutionarily conserved, ATP-dependent chromatin remodelers of the CHD family that play key roles in stem cell differentiation and reprogramming.
Peter Erdelyi +3 more
doaj +1 more source
The Ethics of Germline Gene Editing [PDF]
Journal of Applied Philosophy, 2016 AbstractGermline Gene Editing (GGE) has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, GGE has been strongly resisted. In this article, we analyse the ethical arguments for and against pursuing GGE by allowing and funding its development.
Gyngell, Christopher +2 more
openaire +3 more sources
Characterization of germline development and identification of genes associated with germline specification in pineapple [PDF]
Horticulture Research, 2021 Abstract Understanding germline specification in plants could be advantageous for agricultural applications. In recent decades, substantial efforts have been made to understand germline specification in several plant species, including Arabidopsis, rice, and maize.
Lihua Zhao +13 more
openaire +3 more sources
Defending the genome from the enemy within:mechanisms of retrotransposon suppression in the mouse germline [PDF]
, 2013 The viability of any species requires that the genome is kept stable as it is transmitted from generation to generation by the germ cells. One of the challenges to transgenerational genome stability is the potential mutagenic activity of transposable ...
Richard R. Meehan +9 more
core +1 more source
Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator
Biomolecules, 2021 Many multicellular organisms specify germ cells during early embryogenesis by the inheritance of ribonucleoprotein (RNP) granules known as germplasm. However, the role of complex interactions of RNP granules during germ cell specification remains elusive.
Roshan Priyarangana Perera +6 more
doaj +1 more source
Regulation of the self-renewal vs. differentiation decision in the C.elegans germline [PDF]
, 2011 Adult stem cells are the basis of our reproductive potential, of tissue growth and maintenance, and of wound healing and regeneration. Ageing phenotypes such as hair loss or brittle bones in fact reflect the gradual decline of the proliferative ...
Kalchhauser, Irene
core +1 more source
Transgenerational dynamics of rDNA copy number in Drosophila male germline stem cells
eLife, 2018 rDNA loci, composed of hundreds of tandemly duplicated arrays of rRNA genes, are known to be among the most unstable genetic elements due to their repetitive nature.
Kevin L Lu +4 more
doaj +1 more source
Genetic Analysis of a Family with Multiple Incidences of Prostate Cancer
Case Reports in Oncology, 2022 A family with multiple members diagnosed with prostate cancer was identified, and genetic variants were analyzed. Three brothers were diagnosed with prostate cancer.
Ninghan Feng +5 more
doaj +1 more source
A symbiont's guide to the germline
, 2019 Microbial symbioses exhibit astounding adaptations, yet all symbionts face the problem of how to reliably associate with host offspring every generation. A common strategy is vertical transmission, in which symbionts are directly transmitted from the female to her offspring.
Shelbi Russell +2 more
openaire +3 more sources