Results 181 to 190 of about 246,242 (358)

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang   +6 more
wiley   +1 more source

Longitudinal Relationships between Daily Activity and Hippocampal Atrophy in Japanese Dwellers. [PDF]

open access: yesJ Gerontol A Biol Sci Med Sci
Yuki A   +8 more
europepmc   +1 more source

Cognitive Performance in Early Neuronal Synuclein Disease with Hyposmia but without Motor Disability: Association with Dopamine Deficiency and Isolated Rapid Eye Movement Sleep Behavior Disorder

open access: yesAnnals of Neurology, EarlyView.
Objective To determine the impact of dopamine deficiency and isolated rapid eye movement (REM) sleep behavior disorder (iRBD) on cognitive performance in early neuronal α‐synuclein disease (NSD) with hyposmia but without motor disability. Methods Using Parkinson's Progression Markers Initiative baseline data, cognitive performance was assessed with a ...
Daniel Weintraub   +24 more
wiley   +1 more source

A case series on the effect of lidocaine injection on camptocormia in Parkinson disease: Determination of injection site using muscle hardness tester. [PDF]

open access: yesMedicine (Baltimore)
Yokoi K   +9 more
europepmc   +1 more source

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

open access: yesAnnals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander   +17 more
wiley   +1 more source

Protective Effects of Socioeconomic Status and Lifestyle on Amyloid‐ and White Matter Hyperintensity‐Related Longitudinal Brain Atrophy and Cognitive Decline

open access: yesAnnals of Neurology, EarlyView.
Objective Socioeconomic status (SES) and lifestyle activities (LA) are strongly related, and both are associated with dementia risk. We investigated the influence of SES and LA on brain atrophy and cognitive decline considering amyloid‐beta (Aβ) positron emission tomography and white matter hyperintensity (WMH) load.
Dario Bachmann   +11 more
wiley   +1 more source

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