Results 131 to 140 of about 304,491 (268)

Human Foetal Neuroblasts Exhibit BK Channel‐Dependent Membrane Voltage Oscillations upon Depolarization

Advanced Science, EarlyView.
Primary cultures of neuroblasts isolated from the nucleus basalis of Meynert of 12‐weeks‐old human foetuses were prepared. Whole‐cell patch‐clamp recordings were performed by injecting a depolarizing stimulus current (+500 pA; 500 ms), and the membrane voltage recorded; this stimulus current evoked periodic‐like oscillations in membrane voltage ...
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Federico Tommasi, Sandro Gonzi, Chiara Capacci, Giulia Guarnieri, Pasquale Gallina, Annamaria Morelli, Anna Maria Pugliese   +9 more
wiley   +1 more source

Improving Clinical Outcomes Related to Preeclampsia: Real-World Impacts of Implementation of a Redesigned Approach to Antenatal Care-The Initial Maternity Assessment and Planning (IMAP) Service. [PDF]

Aust N Z J Obstet Gynaecol
Borbolla Foster A, Calvert H, Hinwood M, Kuhne C, Haxton J, Bennett N, Hyett J, Park F.   +7 more
europepmc   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Nipocalimab in Early-Onset Severe Hemolytic Disease of the Fetus and Newborn. [PDF]

Pediatr Discov
Bhatt AH, Nimbalkar SM, Patel DV, Pujara RK.   +3 more
europepmc   +1 more source

SDF‐1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy‐Enhanced Stress Granule Scavenging

Advanced Science, EarlyView.
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long, Meng Wang, Ruolin Mao, Hong Chen, Juepu Zhou, Xiangfei Wang, Zheng Yuan, Ri‐Cheng Chian, Nan Xiao, Qingsong Xi, Yimin Shu, Lei Jin, Lixia Zhu   +12 more
wiley   +1 more source

Maternal metformin treatment in obese pregnant dams normalizes neonatal sensory-motor reflexes. [PDF]

Mol Cell Pediatr
Müller-Limberger E, Frederick B, Hansen S, Wohlfarth M, Janoschek R, Mahabir E, Fischer P, Gründemann D, Kalis S, Alejandre Alcázar MA, Dötsch J, Hucklenbruch-Rother E, Appel S.   +12 more
europepmc   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Markedly Elevated sFlt-1/PlGF Ratios in Atypical Superimposed Preeclampsia Before 20 Weeks of Gestation: A Three-Case Series. [PDF]

J Obstet Gynaecol Res
Ito C, Ogoyama M, Ohkuchi A, Suzuki H, Takahashi H, Fujiwara H.   +5 more
europepmc   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Dietary fiber sources affect reproductive and lactation outcomes and colostrum protein concentration in sows. [PDF]

Trop Anim Health Prod
Lopes IMG, Lima MD, Ferreira SV, Oliveira ACR, Andrade BR, Ribeiro RJSF, Silveira NCDS, Souza AC, Dos Santos LLDR, Ramos LA, Silva FCO, Saliba EOS, Fontes DO.   +12 more
europepmc   +1 more source