BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li +8 more
wiley +1 more source
Targeted Cauterization of Bleeding Cervical Polyps During Pregnancy: A Case Series. [PDF]
Yoneda S +5 more
europepmc +1 more source
A bioactive adhesive hydrogel capable of long‐term uterine retention (>14 days) and local microenvironment modulation is developed by straightforward integration of α‐lipoic acid, L‐arginine, tannic acid, and Lactobacillus johnsonii, which can markedly enhance endometrial repair and restore fertility in a rat model of endometrial injury.
Lifa Chen +9 more
wiley +1 more source
Maternal-Fetal Interplay During Mid-gestation: Inflammatory Biomarker Levels in Maternal Sera, Cord Sera and Placenta. [PDF]
Goin DE +6 more
europepmc +1 more source
Fzd7 Restrains Pink1‐Dependent Mitophagy in Suture Stem Cells to Maintain Cranial Suture Patency
How suture stem cells fail to preserve cranial suture patency remains incompletely understood. Integrated single‐cell and high‐resolution spatial transcriptomic analyses identify reduced Fzd7 expression in Prrx1+ suture stem cells as an early feature of craniosynostosis.
Xinyan Chen +10 more
wiley +1 more source
Gestational Age and Childhood Educational Outcomes in Primary and High School Years.
Schneuer FJ +11 more
europepmc +1 more source
A Scoping Review of 5-HT<sub>3</sub> Antagonist Antiemetic Medication Safety in the Management of Nausea and Vomiting of Pregnancy. [PDF]
Morgan S +6 more
europepmc +1 more source
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He +10 more
wiley +1 more source
Glucocorticoids in pregnancy: a master-switch for fetal maturation.
Tan Y +5 more
europepmc +1 more source
Effects of Chlorogenic Acid-Rich <i>Eucommia ulmoides</i> Extract Supplementation During Late Gestation and Lactation on Maternal Health, Colostrum Composition, and Neonatal Intestinal Development. [PDF]
Zhang Y +6 more
europepmc +1 more source

