Linking DNA damage and senescence to gestation period and lifespan in placental mammals
The mechanism that synchronizes the timing of parturition remains a mystery. Each mammalian species has a specific duration of gestation that is determined by integrated interactions among the mother, placenta, and fetus.
Vijay Pratap Singh +2 more
doaj +1 more source
AbstractSome commentators maintain that gestational surrogates are not ‘mothers’ in a way capable of grounding a claim to motherhood. These commentators find that the practices that constitute motherhood do not extend to gestational surrogates. We argue that gestational surrogates should be construed as mothers of the children they bear, even if they ...
Timothy F. Murphy, Jennifer A. Parks
openaire +3 more sources
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Improving Reproductive Outcomes in PCOS: The Emerging Role of GLP-1 Receptor Agonists
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affecting a significant proportion of women of reproductive age. It is associated with infertility, metabolic abnormalities, and hormonal imbalances, including insulin ...
Adrianna Tabeau +9 more
doaj +1 more source
Effect of the extract of the Plectranthus barbatus (Andr.) Benth in the reproductive performance of Rattus novergicus (Berkenhout, 1769) [PDF]
The supposed use of the extract from Plectranthus barbatus for abortive purposes motivated this investigation about the possible toxic effects of ‘False-boldo’ on the embryos and on the offspring of female Wistar rats. Twenty-seven females and nine males,
Gisélida Maria Baquini da Silva +3 more
doaj
Influence of Rearing System on Sows’ Prolificacy during Gestation
In females reared in individual crates until early control of gestation and in common crates (8-16 heads), prolificacy did not reach values that differ depending on the rearing system: there is a statistically insignificant difference in t-test (p>0.05).
Cornelia Petroman
doaj
WHO-modified Partogram versus Paperless Partogram for Effective Management of Labour: A Research Protocol [PDF]
Introduction: The partograph is a simple, inexpensive tool that provides a continuous pictorial overview of labour. It helps to identify obstructed or prolonged labour and determines when appropriate actions should be taken to prevent complications ...
Saloni, Jyotsana Potdar
doaj +1 more source
Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane +19 more
wiley +1 more source
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
HAEMATOLOGICAL PARAMETERS IN EXOTIC COWS DURING GESTATION AND LACTATION UNDER SUBTROPICAL CONDITIONS [PDF]
Seventy Holstein-Friesian and Jersey cows of different ages kept at the Livestock Experiment Station, Bhunikey (Pattoki), district Kasur, Pakistan were used for this study. These cows were divided into seven groups having 10 animals in each group.
A. SATTAR AND R. H. MIRZA1
doaj

