Results 241 to 250 of about 495,711 (312)

Advancing Pregnancy and Pediatric Science through the NIH Transporter Elucidation Network

Clinical Pharmacology &Therapeutics, EarlyView.
Human gestation is characterized by dynamic changes in maternal physiology and maturation of tissue functions before and after birth. The fetus and neonate are highly dependent upon transfer of maternal nutrients via the placenta and lactating mammary gland, which frequently involve selective membrane transporter proteins.
Joanne Wang, Jashvant D Unadkat, Samuel LM Arnold, John K Fallon, Pouria Fattahi, Dan Dongeun Huh, Nicholas Ieronimakis, Edward J Kelly, Svetlana Lutsenko, Robert M Stroud, Jacqueline B Tiley, Jia Yang, Xujia Zhou, Hao Zhu, Rajini Rao, Kathleen M Giacomini, Lauren M Aleksunes   +16 more
wiley   +1 more source

Association between pre-delivery maternal red blood cell distribution width and birth weight discordance in twin pregnancies: a twin pregnancy cohort study. [PDF]

Front Public Health
Zhang X, Su J, Yue L, Wang H, Bai Z, Wang H, Yi B.   +6 more
europepmc   +1 more source

Medication Use During Breastfeeding—An Understudied Population: A Five‐Year Experience in the Pharmacovigilance Center of Lyon

Clinical Pharmacology &Therapeutics, EarlyView.
Medication use during breastfeeding is common, yet data on drug transfer into breast milk and infant exposure remain limited. This study describes real‐world requests concerning medication compatibility with breastfeeding managed by the Lyon pharmacovigilance center over five years.
Blandine Bertin, Aurore Gouraud, Anthony Facile, Fanny Ledys, Sabrina Pierre, Véronique Pizzoglio, Thierry Vial, Marine Auffret, Marina Atzenhoffer   +8 more
wiley   +1 more source

The INTERGROWTH-21^st Preterm Postnatal Growth Standards are robust across geographical settings and time. [PDF]

Eur J Pediatr
Giuliani F, Gunier RB, Lapillonne A, Rego MAS, Winsey A, Rauch SA, Roggero P, Mendez MCR, Deantoni S, Renau MI, Zarco IAC, Ariff S, Conti CS, Ochieng R, Tuzun F, Asibey J, Shekharappa CB, Tavcioska G, Ismail LC, Menis C, Ryumina I, Nieto R, Agyeman-Duah JNA, Madrid BF, Markelova M, Eskenazi B, Bhutta ZA, Papageorghiou AT, Kennedy SH, Villar J.   +29 more
europepmc   +1 more source

Unbound Intrinsic Formation Clearance of 6β‐Hydroxycortisol Is a Useful Biomarker of CYP3A4 Activity during Pregnancy

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnancy results in multiple physiological changes that impact drug disposition. For example, hepatic CYP3A activity and renal transporter‐mediated clearance increase in late pregnancy, but the time course of these changes across pregnancy is not known.
Aurora K Authement, Mary F Hebert, Emily E Fay, Nina Isoherranen   +3 more
wiley   +1 more source

Proteomic Profiling of Xenobiotic and Nutrient Transporters in Human Placenta of Different Gestational Ages

Clinical Pharmacology &Therapeutics, EarlyView.
The placenta serves a critical role in nutrient uptake and waste elimination for the developing fetus. The placenta is also responsible for the uptake and/or exchange of xenobiotics, including medications, between the maternal and fetal bloodstreams. An estimated 40–80% of women take medications or drugs during pregnancy.
Eric M. Weaver, Ariel Topletz‐Erickson, Edward J. Kelly, Joanne Wang, Nina Isoherranen, Jashvant D. Unadkat, Samuel L.M. Arnold   +6 more
wiley   +1 more source

E-Cervix Assessment of Cervical Softening During Medication Abortion: A Single-Center Observational Study. [PDF]

Int J Womens Health
Li W, Shi H, Lian H, Wang J, Duan J.
europepmc   +1 more source

Longitudinal Trajectories of Autonomic Maturation in Preterm Infants Using Serial 24-Hour Heart Rate Variability Monitoring. [PDF]

Biosensors (Basel)
Sugino M, Kuboi T, Tadatomo Y, Kawaguchi N, Sadamura T, Nakano A, Koyano K, Nakamura S, Takahashi K, Kusaka T.   +9 more
europepmc   +1 more source