Results 41 to 50 of about 495,711 (312)

Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus

open access: yesiScience
Summary: Type 2 diabetes mellitus (T2DM) represents a common complication during pregnancy that affects fetoplacental development. We demonstrated the existence of impaired trophoblast syncytialization under hyperglycemic conditions.
Jie Ning   +6 more
doaj   +1 more source

Diabetes in pregnancy among Sri Lankan women: gestational or pre-gestational?

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012
Introduction: There is an exponential rise in the occurrence of diabetes during pregnancy in South Asia. However data is sparse on the actual pre-gestational diabetes mellitus (PGDM) versus gestational diabetes mellitus (GDM) case-mix.
KGH Jayathilaka   +5 more
doaj   +1 more source

Elevated soluble CD163 in gestational diabetes mellitus : secretion from human placenta and adipose tissue [PDF]

open access: yes, 2014
Recently soluble CD163 (sCD163), a cleaved form of the macrophage receptor CD163, was identified as a macrophage-specific risk-predictor for developing Type 2 Diabetes.
Bastie, Claire C.   +26 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

EPIDEMIOLOGY AND PREVALENCE OF GESTATIONAL DIABETES MELLITUS [PDF]

open access: yes, 2020
Type 2 diabetes mellitus is increasing rapidly all over the world. Women of childbearing age are also affected by obesity and sedentary lifestyle, which are the main causes of this increase. In recent years, epidemiological studies in developed countries
Karakiliç, Ersen
core   +1 more source

Short tandem repeats genotyping of gestational choriocarcinoma – our experiences

open access: yesTaiwanese Journal of Obstetrics & Gynecology
Objective: This short communication demonstrates how short tandem repeat genotyping can identify the origin of gestational choriocarcinoma. Materials and methods: The origin of gestational choriocarcinoma in our three cases was determined using the short
Lajos Gergely   +8 more
doaj   +1 more source

The outcome of Gestational Diabetic pregnancies in the Maltese Islands [PDF]

open access: yes, 2004
Gestational diabetes is generally associated with a higher morbidity and mortality for both the mother and child. Aims: The study aims to assess the outcome indicators of women suffering gestational diabetes and compare these to the remaining obstetric ...
Azzopardi, Joseph   +4 more
core  

Uric acid levels in gestational hypertensive women predict preeclampsia and outcome of small-for-gestational-age infants

open access: yes, 2019
Objective: This study aims to ascertain whether serum uric acid is a suitable predictor of preeclampsia and/or the delivery of small-for-gestational-age infants for women with gestational hypertension.
Xiaobo Zhao (123002)   +2 more
core   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

First trimester glycated hemoglobin in the prediction of gestational diabetes mellitus

open access: yesAl-Azhar Assiut Medical Journal, 2020
Background Gestational diabetes mellitus (GDM) is a serious disease, which may cause complications such as preeclampsia, increased cesarean rates, and macrosomia in mothers and neonates.
Ahmad T.A Fattah   +3 more
doaj   +1 more source

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