Results 71 to 80 of about 349,129 (310)

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Maternal age-specific risks for adverse birth weights according to gestational weight gain: a prospective cohort in Chinese women older than 30

BMC Pregnancy and Childbirth
Background It is unclear whether the effects of abnormal gestational weight gain (GWG) on birth outcomes are differently in women with different maternal ages.
Yidi Wang, Yunhui Gong, Yujie Xu, Xiaoyu Wang, Shufang Shan, Guo Cheng, Ben Zhang   +6 more
doaj   +1 more source

Effectiveness of the Al Qahtani method in estimating gestational age in the context of an alleged illegal abortion : a case report

Padjadjaran Journal of Dentistry
Introduction: Age estimation is crucial in forensic and dental sciences, particularly for determining gestational age in suspected illegal abortion cases.
Ferdy Rijaldi, Yudy Yudy, Eko Prastyo, Nurtami Soedarsono, Mindya Yuniastuti, Juanda Satriyo, Elza Ibrahim Auerkari   +6 more
doaj   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

MOTHERS’ HYPERTENSION AND NEONATAL BIRTH WEIGHT

نشریه پرستاری ایران, 2005
Pregnancy induced hypertension has impacts on birth weight in different gestational ages, and deciding on preventive modalities is mainly based on comprehension of birth weight in different gestational ages.
M. Madadzadeh, Z. Feizi, ES Hajikazemi, H. Haghani   +3 more
doaj  

Spatial epidemiology of gestational age and birth weight in Switzerland: census-based linkage study. [PDF]

, 2019
BACKGROUND Gestational age and birth weight are strong predictors of infant morbidity and mortality. Understanding spatial variation can inform policies to reduce health inequalities.
Egger, Matthias, Skrivankova, Veronika, Zwahlen, Marcel, Kuehni, Claudia, Adams, Mark, Low, Nicola   +5 more
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

Advanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun, Hang Xian, Yunxin Shi, Taotan Yang, Hongyan Shuai, Wenchao Hu, Siying Fei, Miao Xu, Taoyuan Yang, Ruilong Xia, Ting Wen, Fengting Zhu, Yan Fu, Yang Li, Wei Xia, Ran Qian, Yuanying Liu, Zhicheng Tian, Lamei Li, Qian Zhou, Lize Xiong, Rui Cong, Ceng Luo, Shengxi Wu, Xiafeng Shen, Xin Yu, Rou‐Gang Xie, Changgeng Peng   +27 more
wiley   +1 more source

CLINICAL STUDY OF RESPIRATORY DISTRESS SYNDROME IN AL-KADHIMIYA TEACHING HOSPITAL

The Iraqi Journal of Medical Sciences, 2016
Background:Respiratory distress syndrome (RDS) or hyaline membrane disease (HMD) is an acute lung disease of the newborn caused by surfactant deficiency. It is Seen primarily in neonates younger than 36-38 weeks of gestational age weighing less than 2500
Lamia AK Al-Saady, Hayder H Al-Musawi
doaj   +4 more sources

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Lactation is Associated with Accelerated Postpartum Pelvic Floor Muscle Recovery in a Pregnant Simulated Birth Injury Model

Advanced Science, EarlyView.
ABSTRACT Healthy pelvic floor muscles (PFMs) are essential for proper pelvic floor function. The biggest risk factor for PFM dysfunction is injury sustained during vaginal childbirth, yet the factors that facilitate or impair PFM recovery from birth injury remain unknown.
Bianca L. Peña, Khushi M. Diwakar, Hillary K. Tran, Selena Cao, Celeste E. Lintz, Laila N. Hayes, Marianna Alperin, Karen L. Christman   +7 more
wiley   +1 more source