Results 131 to 140 of about 14,270 (275)

Time from pre‐labor rupture of membrane at term to delivery in grand multiparous women

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The effect of parity on labor progression following term pre‐labor rupture of membranes (PROM) has been described, but detailed patterns among grand multiparous women remain unclear. Traditional labor models show accelerated labor with increasing parity, yet few studies have specifically examined PROM latency distributions or ...
Shai Ram   +7 more
wiley   +1 more source

Maternal dyslipidemia during early pregnancy and epigenetic ageing of the placenta

open access: yesEpigenetics, 2019
Disruption of physiological ageing of the placenta is associated with obstetric complications. Altered lipid metabolism is a known trigger of tissue ageing, but the effect of maternal dyslipidemia on placental ageing is not clearly understood.
Deepika Shrestha   +2 more
doaj   +1 more source

Second‐trimester multimetabolite panel for early preeclampsia rule‐out

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins   +7 more
wiley   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

open access: yesiNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng   +3 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

Data‐driven subtyping reveals heterogeneous functional brain development trajectories in preterm infants

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Brain development in preterm infants shows marked heterogeneity, often obscured by group‐level analyses. Between the group‐level and the individual difference, subgroup can model the heterogeneity of early developmental trajectories. To characterize this, we analyzed longitudinal functional connectome data from 90 preterm infants (scanned at ...
Jing Yu   +8 more
wiley   +1 more source

Probiotic consumption reduces alveolar bone loss and kidney damage in pregnant rats with experimental periodontitis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre   +10 more
wiley   +1 more source

Time to initiation of antenatal care and its predictors among pregnant women in Ethiopia: a multilevel mixed-effects acceleration failure time model

open access: yesBMJ Open
Objective To assess the time to initiation of antenatal care (ANC) and its predictors among pregnant women in Ethiopia.Design Retrospective follow-up study using secondary data from the 2019 Ethiopian Mini-Demographic and Health Survey.Setting and ...
Derara Girma Tufa   +5 more
doaj   +1 more source

The impact of breast milk relaxin 2, oxytocin, and insulin‐like peptide 3 on neonatal growth parameters in early life

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives This study aims to quantify the levels of relaxin 2 (RLX2), oxytocin (OXT), and insulin‐like peptide 3 (INSL3) in colostrum (postpartum days 1–5, Visit 1) and mature breast milk (postpartum days 21–35, Visit 2), and to evaluate their associations with neonatal growth outcomes.
Hakan Doneray   +3 more
wiley   +1 more source

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