Results 11 to 20 of about 6,686 (177)

Transcriptomic Characterization of Postmolar Gestational Choriocarcinoma. [PDF]

Biomedicines, 2021
The human placenta shares properties with solid tumors, such as rapid growth, tissue invasion, cell migration, angiogenesis, and immune evasion. However, the mechanisms that drive the evolution from premalignant proliferative placental diseases—called hydatidiform moles—to their malignant counterparts, gestational choriocarcinoma, as well as the ...
Collet C, Lopez J, Battail C, Allias F, Devouassoux-Shisheboran M, Patrier S, Lemaitre N, Hajri T, Massardier J, You B, Mallet F, Golfier F, Alfaidy N, Bolze PA.   +13 more
europepmc   +7 more sources

Precision Diagnosis and Individualized Therapy of Non-Gestational Choriocarcinoma Invading the Corpus Uteri and Cervix: A Case Report and Literature Review. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Non‐gestational choriocarcinoma (NGCC) is a rare type of malignant tumor. Primary lesions are typically detected in the ovary and rarely invade the corpus uteri and cervix. NGCC usually has a poor prognosis due to the difficulty in achieving early and accurate diagnoses because of its rarity.
Ma J, Ma F, Chen T, Lu X, Du Y, Yue X.
europepmc   +2 more sources

Choriocarcinoma in the Cervix: Case Report of a Challenging Differential Diagnosis. [PDF]

Case Rep Obstet Gynecol
Background Primary cervical choriocarcinoma in abortion curettage tissue is extremely rare and represents a diagnostic challenge. It is a serious condition that requires prompt and targeted therapeutic management. This case report describes the diagnostic evaluation, taking into account relevant differential diagnoses and highlighting the importance of
Pfister K, Satler R, Erdin D, Müller A, Meili G, Bode P.   +5 more
europepmc   +2 more sources

Uterine Rupture on Invasive Molar Pregnancy Revealing a Choriocarcinoma: Case Report from a Low-Income Country. [PDF]

Case Rep Obstet Gynecol
Introduction Gestational trophoblastic diseases are rare entities encompassing a wide spectrum of benign and malignant placental pathologies. Uterine rupture is primarily related to a uterine scar and, exceptionally, following an invasive mole or gestational choriocarcinoma.
Zoly RN, Valéry R, Marco RMP, Gabriel RP, Florine R.   +4 more
europepmc   +2 more sources

Incidental Intraplacental Choriocarcinoma in the Setting of Intrauterine Fetal Demise. [PDF]

Case Rep Obstet Gynecol
Gestational trophoblastic neoplasia (GTN) is a rare group of pregnancy‐related diseases involving the abnormal transformation of placental cells with metastatic potential. GTN includes choriocarcinomas, epithelioid trophoblastic tumors, placental site trophoblastic tumors, and invasive moles.
Carlson DK, Smith GK, LeGallo RD, Mills AM, Ring KL.   +4 more
europepmc   +2 more sources

Gestational choriocarcinoma

International Journal of Gynecological Cancer, 2023
Gestational choriocarcinoma accounts for 5% of gestational trophoblastic neoplasms. Approximately 50%, 25%, and 25% of gestational choriocarcinoma occur after molar pregnancies, term pregnancies, and other gestational events, respectively.
Bogani, Giorgio, Ray-Coquard, Isabelle, Mutch, David, Vergote, Ignace, Ramirez, Pedro T., Prat, Jaime, Concin, Nicole, Ngoi, Natalie Yan Li, Coleman, Robert L., Enomoto, Takayuki, Takehara, Kazuhiro, Denys, Hannelore, Lorusso, Domenica, Takano, Masashi, Sagae, Satoru, Wimberger, Pauline, Segev, Yakir, Kim, Se Ik, Kim, Jae-Weon, Herrera, Fernanda, Mariani, Andrea, Brooks, Rebecca A., Tan, David, Paolini, Biagio, Chiappa, Valentina, Longo, Mariangela, Raspagliesi, Francesco, Panici, Pierluigi Benedetti, Di Donato, Violante, Caruso, Giuseppe, Colombo, Nicoletta, Pignata, Sandro, Zannoni, Gianfranco, Scambia, Giovanni, Monk, Bradley J.   +34 more
openaire   +5 more sources

Gestational choriocarcinoma and thyrotoxicosis [PDF]

Cancer, 1979
A case of a 26-year-old woman with metastatic choriocarcinoma and clinical and biochemical thyrotoxicosis is described. This represents the eighth reported case of the association of choriocarcinoma and thyrotoxicosis. Serial monitoring of serum thyroxine (T4) and thyroid stimulating hormone (TSH) levels correlated precisely with the beta sub-unit ...
N R, Anderson, J J, Lokich, W V, McDermott, C, Trey, K R, Falchuk   +4 more
openaire   +2 more sources

An unusual cause of gynaecomastia in a male [PDF]

, 2019
Summary: Beta-human chorionic gonadotropin (βhCG) is normally produced by syncytiotrophoblasts of the placenta during pregnancy and aids embryo implantation.
Bano, G, Beharry, N, Du Parcq, J, Hameed, A, Rehman, T   +4 more
core   +1 more source

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY, Damsky, CH, Fisher, SJ, Grahl, K, Hartman, L, Tarpey, J, Zhang, GY, Zhang, L   +7 more
core   +3 more sources

Expression of mTOR and downstream signalling components in the JEG-3 and BeWo human placental choriocarcinoma cell lines [PDF]

, 2009
This article has been made available through the Brunel Open Access Publishing Fund.Emerging data suggest that nutritional status and body weight are related to reproductive function, and nutrient imbalances during pregnancy lead to changes in the ...
Foster, H, Goumenou, A, Harvey, AJ, Kara, A, Karteris, E, Mparmpakas, D, Zachariades, E   +6 more
core   +2 more sources