Results 61 to 70 of about 7,058 (215)

Placental DEPTOR as a stress sensor during pregnancy [PDF]

, 2011
The author(s) has paid for this article to be freely available under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and ...
Gidron, Y, Goumenou, A, Karteris, E, Mparmpakas, D, Zachariades, E   +4 more
core   +2 more sources

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

The Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass, Kathryn Wolton, Amanda N. Sferruzzi‐Perri   +2 more
wiley   +1 more source

Hypermethylation of SOX2 gene in hydatidiform mole and choriocarcinoma [PDF]

, 2008
This study investigated the expression and methylation profiles of SOX2, a stem cell-related transcription factor, in placentas and gestational trophoblastic disease.
Chan, KYK, Cheung, ANY, Li, ASM, Ngan, HYS, Siu, MKY, Wong, ESY, Zhang, H   +6 more
core   +1 more source

Genetic Characterization and Multidisciplinary Management of Complete Androgen Insensitivity Syndrome: Unveiling a Novel AR Mutation

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT A novel AR frameshift mutation (c.2023_2035del) was identified in a 17‐year‐old phenotypic female with Complete Androgen Insensitivity Syndrome (CAIS). This report emphasizes the necessity of molecular characterization and multidisciplinary management to address diagnosis, surgical timing, and psychological well‐being in disorder of sex ...
Astorino Maria Francesca, Scalise Serena, Di Bella Chiara, La Rosa Maria Angela, Piraino Basilia, Calabrò Marco, Gentile Mattia, Ruggeri Rosaria Maddalena, Esposito Emanuela, Briuglia Silvana, Cannavò Salvatore   +10 more
wiley   +1 more source

Ectopic non-gestational pure choriocarcinoma of the urinary bladder in a young nulliparous female: A diagnostic challenge

Indian Journal of Medical and Paediatric Oncology, 2020
Choriocarcinoma can occur at ectopic extragenital locations such as lungs, mediastinum, retroperitoneum, and even in the brain (nongestational choriocarcinoma).
Rahul Mannan, Sonam Sharma, Saloni Goyal, Tejinder Singh Bhasin   +3 more
doaj   +1 more source

A Rare Case of Primary Pulmonary Choriocarcinoma Metastasizing to the Kidney: Diagnostic and Therapeutic Complexities

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Choriocarcinoma is a highly aggressive malignant tumor composed primarily of cytotrophoblast and syncytiotrophoblast cells without villi and is characterized by beta‐human chorionic (beta‐hCG) gonadotropin production. Although most cases are of gestational origin, rare non‐gestational choriocarcinomas may arise from pluripotent germ
Zorán Belics, Antónia Fürich, Levente Bogyó, Hanna Tihanyi, Mária Madarász, Dorottya Rózsa, Gizella Molnár, Balázs Gérecz, Petronella Hupuczi   +8 more
wiley   +1 more source

Gestational trophoblastic neoplasia presenting as an interstitial ectopic pregnancy

Gynecologic Oncology Reports, 2021
Gestational trophoblastic disease (GTD) is a group of benign and malignant tumors that develop from placental tissue and includes hydatidiform moles and gestational trophoblastic neoplasia (GTN).
C. Toal, A.A. Garrett, S. Kostadinov, M. Boisen   +3 more
doaj   +1 more source

Biological functions of hCG and hCG-related molecules [PDF]

, 2010
Background hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by villous syncytiotrophoblast cells, hyperglycosylated hCG produced by cytotrophoblast ...
Laurence A Cole
core   +1 more source

Modeling human trophoblast, the placental epithelium at the maternal fetal interface. [PDF]

, 2020
Appropriate human trophoblast lineage specification and differentiation is crucial for the establishment of normal placentation and maintenance of pregnancy. However, due to the lack of proper modeling systems, the molecular mechanisms of these processes
Bui, Tony, Horii, Mariko, Parast, Mana M, Touma, Ojeni   +3 more
core   +1 more source

SR‐B1‐Mediated Transplacental Transfer of Hydrophobic Toxicants Disrupts Fetal Development During Barriergenesis

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study maps the spatiotemporal distribution of hydrophobic toxicants and endogenous metabolites in the developing placenta and fetus. By integrating mass spectrometry imaging with snRNA‐seq, we identify SR‐B1 as a key transporter driving early‐gestation xenobiotic transfer and reveal a critical exposure window associated with persistent fetal ...
Yixuan Huang, Hailin Shang, Ling Jiao, Ce Chen, Zehua Liu, Yi Yang, Qiannan Zhang, Song Tang, Xudong Jia, Hui Yang, Yi Wan   +10 more
wiley   +1 more source