Results 201 to 210 of about 742,158 (388)

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn, Jee‐Young Lee, Giorgia Sciacca, Stacy Patterson, Adam Morton, Paul Pun, Walaa A. Kamel, Marina Picillo, Bart Post, Eng‐King Tan, Tamine Capato, Bastiaan R. Bloem, Manon Auffret, Annelien M. Oosterbaan, Willanka Kapelle, Michiko K. Bruno, Lorraine V. Kalia, Jeffrey H. Kordower, Daniela Berg   +18 more
wiley   +1 more source

Synbiotic Nutraceutical Mitigates Gestational Diabetes Effects and Cardiovascular Dysfunction in Rat Offspring

Molecular Nutrition &Food Research, EarlyView.
Maternal supplementation with a synbiotic nutraceutical consisting of jabuticaba peel and Limosilactobacillus fermentum strains during gestational diabetes mellitus (GDM) induces targeted shifts in gut microbial structure and attenuates systemic inflammatory signaling.
Deborah Emanuelle de Albuquerque Lemos, Evandro Leite de Souza, Micaelle Oliveira de Luna Freire, Jaielison Yandro Pereira da Silva, Paulo César Trindade da Costa, Josiane de Campos Cruz, Alisson Macário de Oliveira, João Felipe Mota, José Luiz de Brito Alves   +8 more
wiley   +1 more source

Diagnostic Value of Exome Sequencing in Isolated Polyhydramnios

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield of exome sequencing (ES) in isolated polyhydramnios. Methods This retrospective study included 40 cases of isolated polyhydramnios. All patients underwent screening for gestational diabetes mellitus (GDM) and chromosomal microarray analysis (CMA).
Vered Offen Glassner, Adi Botvinik, Adi Mory, Adi Reches, Karina Krajden Haratz, Britannia Morgan Fleming, Hagit Baris Feldman, Lena Sagi‐Dain, Mordechai Shohat, Rayna Joy Goldstein, Yuval Yaron, Michal Levy   +11 more
wiley   +1 more source

Sex‐specific associations between hypertensive disorders in pregnancy and fetal and placental weight

Pediatric Investigation, EarlyView.
In a US birth cohort, males of mothers with gestational hypertension had higher birthweight Z‐scores, but this association was not found among females. For the fetoplacental weight ratio, any hypertensive disorders during pregnancy were associated with a lower ratio among females only.
Alexandra R. Sitarik, Ganesa Wegienka, Christine C. Johnson, Raminder Khangura, Jennifer K. Straughen, Andrea E. Cassidy‐Bushrow   +5 more
wiley   +1 more source

Comparison of Metformin PBPK Models Incorporating Placental Transfer to Predict Fetal and Maternal Exposure

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling of placental drug transfer is an evolving tool for predicting fetal drug exposure. In this study, a pregnancy‐specific metformin PBPK model was developed, and the following four approaches were evaluated to predict metformin placental transfer: (1) perfusion‐limited model, and permeability ...
Jacqueline B. Tiley, Mattie E. Hartauer, Tajhia L. Whigham, Maïlys De Sousa Mendes, Kim L. R. Brouwer, Mary F. Hebert   +5 more
wiley   +1 more source

Screening for Gestational Diabetes Mellitus: The Potential of MicroRNAs

, 2019
Carmen Pheiffer, Stephanie Dias, Paul Rheeder, Sumaiya Adam   +3 more
openalex   +2 more sources

Mono(2‐Ethylhexyl) Phthalate Induces Inflammatory and Angiogenic Alterations Mediated by the PI3K/AKT Pathway in HTR‐8/SVneo Trophoblastic Cells

Environmental Toxicology, EarlyView.
ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo, Ericka Karol Pamela Almeida‐Aguirre, Mariana Bobadilla‐Bravo, Ismael Mancilla‐Herrera, Alejandra Martínez‐Ibarra, Marco Cerbón   +5 more
wiley   +1 more source

Oral misoprostol (PGE1) vs vaginal dinoprostone (PGE2) for labor induction: individual participant data meta‐analysis of randomized controlled trials

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of oral misoprostol vs vaginal dinoprostone for the induction of labor (IOL) using an individual participant data (IPD) meta‐analysis. Methods We used a Cochrane review and searched Ovid MEDLINE, Ovid Embase, Ovid Emcare, CINAHL Plus, Scopus and ClinicalTrials.gov to identify randomized ...
S. Y. Tan, N. Au, M. D. Peel, J. M. Dodd, A. Deussen, P. A. Le Roux, D. C. Young, F. Tessier, P. Dallenbäch, D. M. R. Croll, M. Patabendige, K. Palmer, W. Li, B. W. Mol   +13 more
wiley   +1 more source

Second-trimester Uterine Artery Doppler Parameters but not Triple Test Analytes, May Predict Gestational Diabetes Mellitus

, 2023
Filiz Yarşılıkal Güleroğlu, Murat Ekmez, Fırat Ekmez, Senem Karacabey, Ali Çetin   +4 more
openalex   +1 more source

First‐trimester Placental Ultrasound (FirstPLUS) study: prediction of fetal growth restriction using OxNNet‐derived first‐trimester placental volume

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives To develop predictive models for fetal growth restriction (FGR) with and without the inclusion of OxNNet‐derived first‐trimester placental volume (FTPV), thereby evaluating the contribution of FTPV to these models and the extent to which FTPV percentile is associated with subsequent FGR.
S. Mathewlynn, L. Nicolatino Starck, D. Wright, Y. Yin, M. Soltaninejad, K. H. Nicolaides, A. Syngelaki, A. Galán Contreras, S. Bigiotti, E.‐M. Woess, M. Swinburne, S. Collins   +11 more
wiley   +1 more source