Results 51 to 60 of about 178,936 (330)

The Correlation Between Maternal Diabetes and Birth Defects [PDF]

, 2015
Diabetes mellitus is one of the most common health problems in the United States, and it is shown to have negative outcomes in infants born to women who are diabetic. Although gestational diabetes mellitus is linked with a few birth defects, research has
Stanton, Erin
core  

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Frequency of Gestational Diabetes Mellitus in Pregnant Women Reporting to a Public Sector Tertiary Care Hospital of Quetta

Pakistan Armed Forces Medical Journal, 2022
Objective: To determine the frequency of gestational diabetes mellitus in pregnant women reporting to a public sector tertiary care hospital and find the association of gestational diabetes mellitus with age. Study Design: Comparative cross-sectional
Majid Latif, Saeed Bin Ayaz, Muhammad Anwar, Muneeba Manzoor, Muhammad Aamir, Syed Aown Raza Shah Bokhari, Maqsood Ahmad   +6 more
doaj   +1 more source

Gestational Diabetes Mellitus

, 2023
Formally recognized by O’Sullivan and Mahan in 1964, gestational diabetes mellitus (GDM) is defined as any degree of hyperglycaemia recognized for the first time in the pregnancy, including type 2 diabetes mellitus diagnosed during pregnancy, as well as true GDM which develops in pregnancy.
Nicolae Gică, Iulia Huluță
openaire   +1 more source

Microcephaly and macrocephaly. A study on anthropometric and clinical data from 308 subjects [PDF]

, 2019
Head circumference is the auxological parameter that most correlates with developmental anomalies in childhood. Head circumference (HC) two standard deviations (SD) below or above the mean defines microcephaly and macrocephaly, respectively.
Corsello G., Mancuso G., Martorana C., Montante C., Notarbartolo V., Piro E., Schierz I. A. M., Vanella V.   +7 more
core   +1 more source

Impact of contraception and IVF hormones on metabolic, endocrine, and inflammatory status [PDF]

, 2020
Assisted reproductive technologies (ART) represent commonly utilized management strategies for infertility with multifactorial causes (including genetically predisposed diseases). Amongst ART, in vitro fertilization (IVF) is the most popular.
Barber, Thomas M., Coussa, Ayla, Hassan, Hayder   +2 more
core   +1 more source

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Effects of gestational diabetes mellitus on risk of adverse maternal outcomes: a prospective cohort study in Northwest Ethiopia

BMC Pregnancy and Childbirth, 2020
Background Gestational diabetes mellitus is a leading medical condition woman encounter during pregnancy with serious short- and long-term consequences for maternal morbidity.
Achenef Asmamaw Muche, Oladapo O. Olayemi, Yigzaw Kebede Gete   +2 more
doaj   +1 more source

Impact of gestational weight gain on obstetric and neonatal outcomes in obese diabetic women [PDF]

, 2015
Both obesity and gestational diabetes mellitus are increasing in prevalence, being a major health problem in pregnancy with independent and additive impact on obstetrics outcomes. It is recognized that inadequate gestational weight gain is an independent
AM Egan, AM Siega-Riz, B Caballero, BE Metzger, CA Carreno, CE Pedreira, Committee on Practice Bulletins--Obstetrics, D Simmons, DW Kiel, E Horosz, H Shaikh, Institute of, M, Inês Gante, JE Park, JM Walsh, Jorge Dores, M Blomberg, MA Kominiarek, Maria C. Almeida, MC Almeida, MC Dennedy, MC Jolly, MW Carpenter, NH Morken, Njila Amaral, S Thangaratinam, SA Lederman, SY Kim, Y Liu, Y Yogev   +29 more
core   +1 more source