Background/objectives: Gestational trophoblastic diseases (GTDs) are rare premalignant and malignant conditions characterized by abnormal proliferation of trophoblastic tissue. They are often asymptomatic but may present with vaginal bleeding.
Giuseppe Gullo +9 more
doaj +1 more source
Response to commentary on "pembrolizumab in gestational trophoblastic neoplasia: systematic review and meta-analysis with sub-group analysis of potential prognostic factors". [PDF]
Dear editor,We appreciate the thoughtful commentary by the authors1 regarding our systematic review and meta-analysis on pembrolizumab in Gestational Trophoblastic Neoplasia (GTN).2 Their constructive feedback underscores important methodological ...
Barcellos M +9 more
europepmc +2 more sources
Gestational Trophoblastic Neoplasia Following Molar Ectopic Pregnancy A Case Report
BACKGROUND: Ectopic molar pregnancy is a gestational trophoblastic disease (GTD) of rare occurrence and therefore not always remembered as a diagnostic possibility.CASE: We describe a case of molar ectopic pregnancy in a primiparous woman who developed ...
Nunes Costa, Olivia Lucia +3 more
core +2 more sources
Current Evidence on Immunotherapy for Gestational Trophoblastic Neoplasia (GTN)
SIMPLE SUMMARY: Gestational trophoblastic neoplasia (GTN) is a rare tumor group that arises from the malignant transformation of placental tissue. Based on the evaluation of International Federation of Gynecology and Obstetrics (FIGO) anatomic staging ...
Bergamini, Alice +15 more
core +1 more source
Placental Site Trophoblastic Tumor: Two Rare Case Report and Literature Review Within a Decade
This case report presents two rare cases of placental site trophoblastic tumor (PSTT) with detailed clinical presentations, diagnostic challenges, and long-term treatment outcomes.
Yiqi Guan +3 more
doaj +1 more source
A delay on diagnosing Gestational Trophoblastic Neoplasia (GTN) may cause increase of morbidity to the patient. The important things that OBGYN usually forgot is that GTN may develop not only from previous molar gestation (50-60%), but also from ...
Olivia Widyanti +3 more
core +2 more sources
Leptomeningeal spread of gestational trophoblastic neoplasia in a 19-year old woman
Gestational trophoblastic neoplasia (GTN) with brain metastasis is usually seen in patients with advanced disease. Ten percent of metastatic gestational trophoblastic disease involves the brain and spinal cord, most often manifesting as an intracerebral ...
Nnamdi I. Gwacham +3 more
doaj +1 more source
The evolution of methotrexate as a treatment for ectopic pregnancy and gestational trophoblastic neoplasia: a review. [PDF]
Methotrexate was developed in 1949 as a synthetic folic acid analogue to compete with folic acid and thus interfere with cell replication. While initially developed as a potential treatment for acute lymphoblastic leukaemia, a serendipitous observation ...
Skubisz, MM, Tong, S
core +1 more source
Invasive mole of the uterus: A description of two cases managed by hysterectomy
Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumors. Gestational trophoblastic neoplasia (GTN), is recognized as the most curable gynecologic malignancy.
Ahmed Samy El-agwany +1 more
doaj +1 more source
Gestational trophoblastic neoplasia in the 1990s.
Version of ...
openaire +2 more sources

