Results 91 to 100 of about 4,549 (210)

A Rare Case of Choriocarcinoma With Myometrial Invasion Mimicking Invasive Mole: Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Gestational trophoblastic neoplasia (GTN) comprises a group of rare tumors arising from placental trophoblastic tissue, including choriocarcinoma and invasive mole. We present a rare case of choriocarcinoma with isolated myometrial invasion in a 30‐year‐old woman with a history of molar pregnancy and term delivery.
Shaghayegh Vandadi, Afsaneh Tehranian, Nasim Zarifi, Akram Seifollahi, Amirhossein Hajialigol   +4 more
wiley   +1 more source

Genomic Imprinting and Cancer: From Primordial Germ Cells to Somatic Cells [PDF]

, 2006
Imprinted genes are a subset of genes that are expressed from only one of the parental alleles. The majority of imprinted genes have roles in growth regulation and are, therefore, potential oncogenes or tumour suppressors. Cancer is a disease of aberrant
Adele Murrell
core   +1 more source

Placental Mesenchymal Dysplasia: How to Approach the Diagnosis as Early as the First Trimester? A Case Report and a Review

Clinical Case Reports, Volume 13, Issue 10, October 2025.
Transabdominal ultrasound performed at 9 weeks and 6 days of GA showing an anterior, thickened and multi‐cystic appearing placenta. (A) Ultrasound performed at 27 weeks of GA showing an apical cystic zone evoking a thrombotic formation. (B) Ultrasound performed at 34+4 weeks of GA, additional thrombosis zone in one of the dilated vessels of the ...
Smalaj Margheret, Törnblom Paulander Sara, Tessier Aude, Buxant Frédéric, Cassart Marie, Gajewska Kalina   +5 more
wiley   +1 more source

Gestational Trophoblastic Disease: Diagnostic and Therapeutic Updates in Light of Recent Evidence: A Literature Review

Medicina
Background/objectives: Gestational trophoblastic diseases (GTDs) are rare premalignant and malignant conditions characterized by abnormal proliferation of trophoblastic tissue. They are often asymptomatic but may present with vaginal bleeding.
Giuseppe Gullo, Marinì Satullo, Eleonora Conti, Silvia Ganduscio, Elena Chitoran, Zoltan Kozinszky, Karolina Kowalcze, Robert Krysiak, Valentina Billone, Gaspare Cucinella   +9 more
doaj   +1 more source

Distinct gestational trophoblastic neoplasia - different entities, specific management [PDF]

, 2017
Gestational trophoblastic diseases are abnormalities of the trophoblastic tissue development. They have Β-hCG as tumour marker, similar clinical manifestations but different pathological features, management and prognosis.
Brandão, Pedro, Costa, Fernanda, Pinto, Ana Rita, Silva-Rocha, Juliana   +3 more
core   +2 more sources

Exploring the interdependencies of research funders in the UK [PDF]

, 2014
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P, Farrell, C, Garau, M, Grassano, N, Hernandez-Villafuerte, K, Hopkins, M M, Hutton, J, Lang, F, Mawer, A, Pateman, C, Rotolo, D, Shah, K, Sharp, T, Sussex, J   +13 more
core   +1 more source

Alteration of proliferation and apoptotic markers in normal and premalignant tissue associated with prostate cancer [PDF]

, 2006
Background Molecular markers identifying alterations in proliferation and apoptotic pathways could be particularly important in characterizing high-risk normal or pre-neoplastic tissue. We evaluated the following markers: Ki67, Minichromosome Maintenance
Vijayalakshmi Ananthanarayanan, Ryan J Deaton, Ximing J Yang, Michael R Pins, Peter H Gann, BJ Braakhuis, BJ Braakhuis, DP Slaughter, WA Franklin, MP Copper, CR Porter, JI Epstein, L Zeng, V Padmanabhan, MV Meng, RN Winter, DG Bostwick, MI Johnson, NR Mucci, P Tamboli, A Dutta, A Freeman, P Chatrath, K Rodins, DC Brown, H Takisawa, RB Myers, R Montironi, WC Xue, BB Wolf, V Kumar, F Yamasaki, L Leoncini, JH Sohn, AJ O'Neill, S Zanotti, WR Duan, B Grasl-Kraupp, MM Kockx, S Baltaci, SD Catz, O Haussler, M Colombel, MP Tabor, DL Ellsworth, L Shen, V Ananthanarayanan, YP Yu, R Dhir, G Ayala, H Bonkhoff, R Montironi, T Mairinger, PH Bartels, R Montironi, A Raimondi, SH Barsky   +56 more
core   +2 more sources

Low-risk gestational trophoblastic neoplasia outcome after treatment with VMP regimen from 2005 to 2017

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: To evaluate the efficacy and toxicity of VMP regimen applied to the patients with low-risk gestational trophoblastic neoplasia (LR-GTN) treated in Anhui provincial hospital.
Chen-Chen Zhu, Han-Yuan Liu, Ying Wei, Zhen Shen, Li-Li Qian, Wei-Guo Song, Juan Wang, Da-Bao Wu, Xue-Fen Zhang, Ying Zhou   +9 more
doaj   +1 more source

Is genetic analysis useful in the routine management of hydatidiform mole? [PDF]

, 2017
Complete hydatidiform mole and partial hydatidiform mole are two abnormal conceptuses that may be identified by clinical, ultrasonographic, gross morphological, histological, and genetic characteristics.
Billieux, Marie‐Hélène, Blouin, Jean‐Louis, Dahoun, Sophie, Petignat, Patrick, Vassilakos, Pierre   +4 more
core  

Mechanisms of matrix metalloproteinase-2 (mmp-2) transcriptional repression by progesterone in jar choriocarcinoma cells [PDF]

, 2009
Background Although the MMP-2 promoter lacks a canonical progesterone response element (PRE), the hormone inhibits MMP-2 expression and is part of treatment protocols in gynecological invasive pathologies, including endometriosis and endometrial ...
Shlomit Goldman, David H Lovett, Eliezer Shalev   +2 more
core   +2 more sources